plz help to get this paper: J. Biol. Chem. 2011 286: 40219-40231. First Published on September 23, 2011, doi:10.1074/jbc.M111.259440. PMID: 21949126. Mail me to ranjijo@gmail.com
An oxidative cross-dehydrogenative-coupling reaction in water using molecular oxygen as the oxidant: vanadium catalyzed indolation of tetrahydroisoquinolines - Chemical Communications (RSC Publishing) - http://pubs.rsc.org/en...
Sometime back, i used V2O5, O2, in toluene to do alcohol oxidation. If i remember correctly R. A. Sheldon used this system in early 80's for various oxidations. The conditions are very old and well known, just two will-work-for-sure substrates. But cant be in Chem Commun.
- Ahamed
10.1002/anie.201104017 Another rxn on this ring system from Maruoka. Elaborate catalyst system and substrate but which delivers something challenging. One to reference.
- Matthew Todd
from Bookmarklet
Teasing one. Must have worked hard to optimize this one.
- Ahamed
A Dual-Catalysis Approach to the Asymmetric Steglich Rearrangement and Catalytic Enantioselective Addition of O-Acylated Azlactones to Isoquinolines
http://pubs.acs.org/doi...
Construction of ISQ ring with different strategy. Possibility of generating chiral center at 1-position using chiral bronsted acid, a well known chemistry developed by Rueping.
- Ahamed
Pyrido[3,4-e]-1,2,4-triazines and related heterocycles as potential antifungal agents, http://pubs.acs.org/doi..., J. Med. Chem., 1989, 32 (11), pp 2474–2485
Yes do have acess to almost all the journals, but some years i cant acess. dont know why. But i can request form library, it will take couple of days.
- Ahamed
Synthesis and In Vivo Imaging of a 18F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method, Angew. Chem. Int. Ed.,
http://onlinelibrary.wiley.com/doi...
Highly Efficient Synthesis of Polysubstituted 1,2-Dihydroquinolines via Tandem Reaction of α-Ketoesters and Arylamines Catalyzed by Indium Triflate,
ACS catalysis, http://pubs.acs.org/doi...
Abstract: In 2010, GlaxoSmithKline published the structures of 13533 chemical starting points for antimalarial lead identification. By using an agglomerative structural clustering technique followed by computational filters such as antimalarial activity, physicochemical properties, and dissimilarity to known antimalarial structures, we have identified 47 starting points for lead optimization. Their structures are provided. We invite potential collaborators to work with us to discover new clinical candidates.
- Ahamed
Indeed - ours is one of those series. Such a spectacular paper on so many levels.
- Matthew Todd
Methazonic acid (2-Nitroacetaldehyde oxime): Anyone ever handled methazonic acid? it is prepared by mixing 10N NaOH and nitromethane. It is explosive in nature, i need to make it for one of my project. Some suggestion needed.
Exploring the Oxidative Cyclization of Substituted N-Aryl Enamines: Pd-Catalyzed Formation of Indoles from Anilines - Neumann - 2011 - Chemistry - A European Journal - Wiley Online Library - http://onlinelibrary.wiley.com...
Kielland, Nicola (2010). "Synthesis of Heterocycles via Multicomponent Reactions II Recent Developments in Reissert-Type Multicomponent Reactions" in Synthesis of Heterocycles via Multicomponent Reactions II (3-642-15454-9, 978-3-642-15454-6), (p. 127). Berlin, Heidelberg: Springer.
DOI: 10.1007/7081_2010_42