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Andrew Clegg › Likes

Björn Brembs
Iddo Friedberg
Protein function: how do we know that we know what we know? http://bytesizebio.net/index...
Yet another example of what you can do with open data. - Daniel Mietchen
How come http://biofunctionprediction.org/ and http://www.biofunctionprediction.org/ go to completely different sites? Bit confusing for users :-) - Andrew Clegg
Something else that just occurred to me -- you might find South African researchers react a bit weirdly to the name CAFA. In SA, calling something CAFA would be like calling something NIGA in America... - Andrew Clegg
Andrew: thanks for the www alert. I fixed that in the DNS manager. (Give the fix a couple of hours to percolate through the 'tubes). As for the name: well, sorry, but any combination of syllables may be offensive in one language or another. The name actually comes from Hebrew: cafa is slang for "slap". - Iddo Friedberg
Indeed -- I'm not given to offendedness (s that a word?) or rampant political correctness at all, just thought you might want to know :-) Have directed colleagues who do function prediction to the site, they seemed pretty keen - Andrew Clegg from twhirl
Andrew: thanks for the PR! - Iddo Friedberg
Alexey
LOL god: Too stupid to understand science? Try religion. - http://lolgod.blogspot.com/2010...
LOL god: Too stupid to understand science? Try religion.
ehh, gotta say I'd not-like this if I could. I know plenty of smart people (scientists even) who happen to be religious, and plenty of stupid scientists. And I'd forgive the generalization if the rest of it were funny or insightful, but frankly it's not. my two cents... - Andrew Su
indeed about 50% scientists are religious, but I think they should take a joke. If they will draw funny cartoon about non-religious scientists I'd appreciate - Alexey
Love it! Hilarious :-) But may indeed not work both ways ... - Björn Brembs
http://ff.im/fIv4S It is not funny at all, Alexey. This picture insult us. Made this joke in Russia and you will be in the prison. - Denis Stankov
"If your brain is too small to hold two thoughts in it at the same time, try being a non-religious scientist." Alexey, you will appreciate this. (I can see the cartoon in my mind's eye, but would rather not spend time drawing it to insult all non-religious scientists just because one of them insulted me and claims he will find this funny.) - Ruchira S. Datta
I recall someone once said that the human mind is not limited in its capacity to hold mutually exclusive opinions. :-) - Björn Brembs
I'm with Andrew. I myself don't quite see how a religious worldview is compatible with being a scientist by trade, but then I don't really understand QED either. And I'm not the dumbest scientist I know. The argument I always get back is that "those religious types" are trying to shove their beliefs down our throats etc etc. I get why that's a bad thing; I don't get why doing it back is a good thing, or how this kind of sneering is supposed to solve the religious expansionism problem. - Bill Hooker
You're going to have to explain that "mutually exclusive" bit to me very slowly and clearly, Björn. After all, I'm stupid. Oh, and I'd appreciate it if your explanation applies to my specific religion. Since the cartoon generalizes across all religion, that should not be a problem for you. - Ruchira S. Datta
@Ruchira, I even didn't think that simple sharing picture about science-religion could insult someone. I think if author of this cartoon aimed to poke religious people, it could be insulting for some of them. When i was sharing this i didn't aim to poke and insult religious people. If it happened, probably I was wrong when was sharing it here. Well, you made me think. - Alexey
Okay thanks Alexey. - Ruchira S. Datta
I'm so happy that Alexey was changed today. - Denis Stankov
@ruchira: the quote means that the people you mentioned don't exist as we all can hold two thoughts at the same time - some even mutually exclusive ones. - Björn Brembs from iPhone
All right, Björn, I will spell out my cartoon for you. On the left there is a smiling person with a large brain. The brain is visible inside the large forehead of the person. Inside the brain are written the words "Religion" and "Science". They fit there. On the right there is a person with a small brain visible. Inside it is written the word "Science". The person is frowning and trying... more... - Ruchira S. Datta
this would be funny as wel :) it's just a cartoon - Rajarshi Guha
Now Ruchira's cartoon I would like. Yeah, potentially offensive, but to me it's a new and interesting take on some aspect of society. Thought provoking, biting social commentary... But I find the cartoon above neither funny nor new, and in the absence of either, then I think Bill's label of "sneering" is pretty spot on. - Andrew Su
@Ruchira: lol :-) No need to explain it to me, I'm not the one who's not getting it, dude - calm down, breathe and think a little before you write. You're getting the whole story the wrong way around. And please don't embarrass yourself more by asking me to explain it to you, I would do it. :-) No offense! - Björn Brembs
For the record, I don't like Ruchira's cartoon any better. I understand that R felt provoked, but I'm sure the author of the first cartoon was responding to some perceived trespass as well. "He started it" hasn't really worked for me since I was about four years old. - Bill Hooker
So, funny! - Mary Spiro
Wait I especially love the orbital versus the halo, nice touch! - Mary Spiro
Eric Jain
The Manga Guide to Molecular Biology - http://oreilly.com/catalog...
manga.jpg
Masaharu Takemura is Japanese biotechnologist and write biotechnology books easily. http://www.rs.kagu.tus.ac.jp/takemur... - Ami Iida
Iddo Friedberg
"Do not wear Axe Body Spray. In fact, that's sound advice even outside of the context of a poster session. It's a godawful smell that simply advertises any number of inadequacies, if not all of them." - Iddo Friedberg
Wow, if my grad-school 'research skills' seminars had been even half as entertaining as this page, I'd have gone to more than two of them... - Andrew Clegg
Cesar Sanchez
Parasites... I prefer to call us "symbionts", following De Bary http://is.gd/4XLe8 - Dilbert comic strip 11/17/2009 - http://dilbert.com/strips...
Parasites... I prefer to call us "symbionts", following De Bary http://is.gd/4XLe8 - Dilbert comic strip 11/17/2009
Its the DJ business :) - Sean Seaver
Iddo Friedberg
Two Good Reasons To Always Read the Methods Section of a Scientific Paper - Boing Boing - http://www.boingboing.net/2009...
Michael Nielsen
nice solution to the multiple author problem - Jean-Claude Bradley
Really great story! Congrats Michael, Timothy, and the rest of the team! - Steve Koch
Michael Nielsen
Question and answer site for mathematics, with quite a bit of serious activity at a high level. - Michael Nielsen
stackoverflow and serverfault are incredibly useful sites so it's nice seeing their codebase being used for something else - Andrew Clegg
Alejandro Montenegro
Hey, the Ig Nobel Prize winners are in: http://improbable.com/ig...
In re: The Chemistry Prize: For goodness sake, why would you want to turn tequila into diamonds? That's devaluing it ;) - Todd Harris
ROFL.... so true... - Alejandro Montenegro
Congrats to Newcastle Uni :) Glad to be from a Uni where someone's won an IgNobel! Newcastle press release here: http://www.ncl.ac.uk/press... - Allyson Lister
Donnie Berkholz
Early Risers Crash Faster Than People Who Stay Up Late: Scientific American - http://www.scientificamerican.com/article...
"An hour and a half after waking, early birds and night owls were equally alert and showed no difference in attention-related brain activity. But after being awake for 10 and a half hours, night owls had grown more alert, performing better on a reaction-time task requiring sustained attention and showing increased activity in brain areas linked to attention. More important, these regions included the suprachiasmatic area, which is home to the body’s circadian clock. This area sends signals to boost alertness as the pressure to sleep mounts. Unlike night owls, early risers didn’t get this late-day lift." - Donnie Berkholz from Bookmarklet
I knew it! - Fossil Huntress
I always secretly knew we night owls were better adapted than those crazy-up-before-dawn people! - Lindsay
Posted at 11:15 pm local time ... and still going strong! - Donnie Berkholz
is SA late to this - that paper came out a few months ago. There was some good coverage of it, e.g., http://sciencenow.sciencemag.org/cgi... - Bora Zivkovic
For the record, I'm liking this at 12:32 AM Eastern. - Chris Lasher
This reminds me, it's 5:58am here... Off to bed. - Ricardo Vidal from iPod
Glad to see one positive about us night owls. Many are touting the harm of going against circadian cycle. Have been a day sleeper for ten plus years-no harm no foul. - Celt MacGann
I know this feeling... Have had far too many days where my brain only really starts to wake up at 6pm, just in time to leave office because girlfriend/social life/other commitments are calling - Andrew Clegg
This is the most visited post on all of my blogs at all times: Everything You Always Wanted To Know About Sleep (But Were Too Afraid To Ask): http://scienceblogs.com/clock... Four years old but still pretty much up to date. Explains it all. - Bora Zivkovic
BUT...us early birds get a whole day's work done in that first hour and a half...lol - Mary Canady
@Bora spectacular post! Love the wealth of information and dearth of politics :) Feel less guilty and more hopeful already. Here's one of my favorite lines from Bora's post: 'Of course, all of the above are the strategies to shift your clock to a "socially accepted" phase. But you are not crazy or sick. It is the societal pressure to get up at a certain time that is making you sick. Try... more... - Steve Koch
@ Bora -- loved the post, too! I especially appreciated the discussion of light -- I spent a few months reading up on the impact of light, and a Science channel feature on biochronology a few months ago found that very bright light did a lot to help Alzheimer's patients and that planning around an individual's circadian rhythm could ease the side effects of chemo while increasing... more... - Mickey Schafer
That was my first true science post, from January 2005, the one that showed me there is interest in this and I could move from blogging politics to blogging science. I posted it on a brand new blog that nobody knew about, just set up, and the next day it was linked by BoingBoing, Andrew Sullivan and others. Even today, it is still my most visited post ever (and that counts ONLY the... more... - Bora Zivkovic
Björn Brembs
Just got this link from Elsevier. Looked up some of the prices: First page of my article as a small poster: 25€+tax/shipping. Printed issue with my paper in it: 30€. 50 offprints of my article 300€. Checking the download stats of the article PDF on my homepage: priceless! - Björn Brembs from Bookmarklet
Iddo Friedberg
A FLORA of Protein Structure to Protein Function - http://bytesizebio.net/index...
I presented this paper in my lab meet, but I was not able to find the expansion of FLORA in the paper. - Khader Shameer
I work in the Orengo group -- but not on FLORA, this was all before I arrived. Thanks for the article, I've sent the link around the lab. PS see also comments on article - Andrew Clegg
Anthony Phan
Google Algorithm Predicts When Species Will Go 404, Not Found | Wired Science | Wired.com - http://www.wired.com/wiredsc...
Google Algorithm Predicts When Species Will Go 404, Not Found | Wired Science | Wired.com
Extinction = 410 (Gone) - Eric Jain
Michael Kuhn
"Potter discovered, however, that geographic location alone could determine whether a drug bested placebo or crossed the futility boundary." - Michael Kuhn
"In one study, Benedetti found that Alzheimer's patients with impaired cognitive function get less pain relief from analgesic drugs than normal volunteers do. Using advanced methods of EEG analysis, he discovered that the connections between the patients' prefrontal lobes and their opioid systems had been damaged. Healthy volunteers feel the benefit of medication plus a placebo boost." - Michael Kuhn
My comment on another thread: Think for a minute about what the placebo response is. It is partly a reflection of "things will get better anyway." The rest of it is "someone is ill whose body had all that was necessary to heal itself." So if placebo becomes more effective, either (a) the spontaneous recovery rate is going up -- which I don't think it is because diagnoses require... more... - Daniel Dulitz
Daniel, what's traditional medicine? - Andrew Clegg
Andrew, it's practiced by people called anything from healers to shamans to "witch doctors." It's popular in the East (i.e. "Chinese traditional medicine"), it often uses herbs, touch, energy work, etc. - Daniel Dulitz
How is all that stuff one tradition? And wasn't the concept of "traditional Chinese medicine" a political invention from Mao after WWII? (see e.g. http://bit.ly/SDdt0 ) - Andrew Clegg
Egon Willighagen
does anyone else think its weird that they're calling these things robots? seems like they're dragging us into the future... - Mary Canady
LOL, it follows naturally (for me, at least) from how people call auto-responding IM services or IRC scripts bots. - Mr. Gunn
Cesar Sanchez
Paint my thoughts (drawing in science, Ramon y Cajal, GFP, brainbows) - Protein Spotlight - http://www.expasy.org/spotlig...
Paint my thoughts (drawing in science, Ramon y Cajal, GFP, brainbows) - Protein Spotlight
For those unfamiliar with Santiago Ramon y Cajal, see Wikipedia entry (http://is.gd/2wMPJ). I also recommend this assay in LabLit: "Dr. Bacteria: The strange science fiction of Santiago Ramón y Cajal" (http://is.gd/2wMY4). - Cesar Sanchez
Berci Mesko, MD
How Do Scientists Really Use Computers? » American Scientist - http://www.americanscientist.org/issues...
"As for what occupied the most of our respondents’ time, coding and debugging took first place." This doesn't seem typical for any-given-average scientist! Surely: checking email, writing papers in Word, analysing data in Excel, and doing domain-specific stuff like working with the control software for their instruments? - Andrew Clegg
Chris Miller
Encouraging good development practices for non-professional programmers? - Stack Overflow - http://stackoverflow.com/questio...
"I collaborate with a number of scientists (mostly biologists) who develop software, databases, and other tools related to the work they do. . . . Does anyone have any suggestions for how to persuade people whose primary job isn't programming that it's of benefit to their community for them to be more open with the tools they've built?" - Chris Miller from Bookmarklet
I wish I had enough karma to vote down that first answer (the one about Perl) - Deepak Singh
I wish I remembered my password to my other account to vote up that answer (the one about Perl) XD - Paul J. Davis
lol - Deepak Singh from IM
People shouldn't be getting grants without having a plan for sustainable software development and long term data storage. I wonder if grant reviewers have gotten more clueful about such issues in the past few years? - Eric Jain
Eric ... Alas no. Although they are beginning to ask the right questions - Deepak Singh from iPhone
Sure would be interesting to see the funding agencies require posting code developed using public money to a repository somewhere and then have journals require links to code before publication similar to genome papers. Even something as simple as versioned tarball hosting. - Paul J. Davis
Paul Bacchus
Should biologists study computer science? - Ars Technica - http://arstechnica.com/science...
Liked... But I disagree with the suggestion that comp. biol. is the same as in silico modeling. - Andrew Clegg
Every computational method has different sources of error, just as every experimental technique does, with false positive rates and false negative rates. If you have no idea how it works you'll just have to trust it blindly. - Ruchira S. Datta
Iddo Friedberg
Calling dibs on the phrase: "Postdoc traumatic stress disorder"
I still have nightmares... - Iddo Friedberg
Neil Swainston
Might get more synergy if it is on git? - Jason Stajich
Left a comment... I think this is good news: 'they' now seem to agree that we are doing science, and that someone may steal our science.... Good, progress, good. - Egon Willighagen
I'm not entirely sure what I'm doing *is* science. That's not to say that that rings true for all bioinformatics. - Neil Swainston
Abhishek Tiwari
Mendeley- Most read authors overall
most_read.png
for "Defrosting the digital library: bibliographic tools for the next generation web" - Abhishek Tiwari
huuu..surprisingly no like for this. - Abhishek Tiwari
Don't really use Mendeley - but does this mean of all the people using mendeley, that their most-read author is Duncan? Impressive - wonder what the distribution of research areas is in Mendeley - lots of people in CS/bioinformatics, it looks like. :) Thanks for sharing! - Allyson Lister
This made me smile when I set up a Mendeley account last week. Allyson, the two biggest groups of users on Mendeley are Biological Science (3838 users) and Computer and Information Science (3430 users) - Daniel Swan
Jim Hardy
Still cracking up: "18 flavour attributes (sweet, sour/acid, tuna, herbal, spicy, soy, salty, cereal, caramel, chicken, methionine, vegetable, offaly, meaty, burnt flavour, prawn, rancid and bitter) and four texture dimensions (hardness, chewiness, grittiness and viscosity) were generated to describe the sensations elicited by 13 commercial pet food samples." - Jim Hardy from Bookmarklet
Comedy gold. BTW WTF does MET taste like anyway?!? - Andrew Clegg
Bill Hooker
In discussion here (http://i9606.blogspot.com/2009...?) I mentioned that I won't review for toll-access journals, only OA ones (or those that don't embargo author postprints, if any such exist). Benjamin suggested that a public declaration might be useful -- any ideas? For instance, would you sign such a declaration?
I have been thinking about this too, but decided not to do this just yet... - Egon Willighagen
Love this idea! Can anyone think of any downside to doing this / to not reviewing? My understanding is that reviewing does not measurably add to your academic reputation - but then I never went past postdoc - Lisa Green
I am prepared to sign, but I'm afraid we'd need some bigger fish to make a compelling case out of this. Perhaps some of the people in the editorial boards of PLoS or BMC? Bora, Peter - can you hear me? - Daniel Mietchen
Not fair to ask PLoS, BMC et al to take a stand on this -- conflict of interest! - Bill Hooker
One possible downside: if you're junior, reviews often get handed down the food chain. The declaration might need a weasel-paragraph about continuing to do such reviews when requested by PI/boss. - Bill Hooker
The main downside as a young researcher is to mark yourself out as a maverick who doesn't play by the accepted rules. That can obviously be a plus as well as a minus but be prepared to play the part you choose I would say. - Cameron Neylon
I do not think Open Access journals are disruptive or worth fighting for. They are just continuing the old model with a twist. See my post http://www.daniel-lemire.com/blog... - Daniel Lemire
Nicely put, Daniel. - Daniel Mietchen
What about declaring "I will engage in post-publication review" instead of negating to engage in traditional pre-publication review schemes? Of course, suitable schemes for the post variant would still have to be worked out, but they are somewhat "in the air" (cf. http://ff.im/43iKP or Google Wave or our blog 3 proposal). - Daniel Mietchen
That was a good post Daniel, but I think peer review is a necessary evil, unless we can come up with a versioned web based peer review system. Kind of like a blog peer reviewed by the comments it receives. - Brian Krueger - LabSpaces
I am aware that there is more to OA than Gold, and that green OA can actually help to get post-publication review schemes rolling if we can find transparent ways to provide incentives for post-review schemes, and to aggregate the ratings for each item, author and reviewer. - Daniel Mietchen
@Daniel (Lemire), you can use the arXiv and presumably face no penalty, but in biomed there are few journals that will accept a paper which has been placed on a public preprint server, so your disruptive solution is discipline-specific. One could try saying "the hell with journals" but your concern over the number of available OA journals and their standing indicates that you are well aware that game is not going away any time soon. - Bill Hooker
Also, the declaration need not, as I said in the OP, restrict one to Gold OA. If a journal's policies are compatible with embargo-free postprint Green, that is fine with me also. I had a look around and some, but not all, SHERPA/RoMEO Green publishers meet this condition (http://www.sherpa.ac.uk/romeo...). - Bill Hooker
Abhishek Tiwari
Abhishek Tiwari
EndNote maker's lawsuit over open-source Zotero dismissed - Ars Technica - http://arstechnica.com/web...
"The makers of the commercial reference management application EndNote have sued an open source alternative called Zotero, claiming that its ability to import EndNote files violated its creators' software license. That case has now been dismissed, leaving Zotero in the clear." - Abhishek Tiwari from Bookmarklet
The comments are pretty interesting, too -- some stuff on the comparative value of commercial versus open source that the FF community would probably enjoy. - Mickey Schafer
I presume you mean, Mickey, this one (I am jsut quoting here--I am a lady!), "Good, let the competition F EndNote up the rear." - Hope Leman
Actually, hope, I was thinking more on just the open source stuff:-) -- but I had to read that one a couple of times before I figured it out -- apparently I spend too much time in polite company -- need to hang out in the comment section at DrugMonkey more often! - Mickey Schafer
I wonder if this was that stupid software that injected patent notice text into the files it produced, as well as into OLE objects embedded into files created in other software... - Tyson Key
Iddo Friedberg
Excellent and gross in equal measures - Andrew Clegg
Abhishek Tiwari
OA publisher accepts fake paper :The Scientist [10th June 2009] - http://www.the-scientist.com/blog...
"Davis told The Scientist that he got the idea for this "little experiment" after receiving scores of spam emails soliciting article submissions and invitations to serve on editorial boards of open access journals from Bentham Science Publishers, TOISCIJ's publisher. According to its website, Bentham publishes "200 plus open access journals" that cover disciplines from bioinformatics and pharmacology to engineering and neuroscience. "One of the things that made Bentham catch our eye," Anderson said, "was that they were so aggressively soliciting manuscripts." " - Abhishek Tiwari from Bookmarklet
An OA publisher needs to be open about whether this MS was peer-reviewed. I think the old Sokal paper was, right? - Matthew Todd
@Matthew did u mentioned about this one http://www.physics.nyu.edu/faculty... - Abhishek Tiwari
He says he didn't get any reviewer comments back, so probably not. - Mr. Gunn
MrG - I meant for the Sokal paper, were there any ref comments? i.e. are these different cases? - Matthew Todd
Quality stuff, marred only by their complete misunderstanding of 'context-free grammar' in the blog post. Sorry, linguistics nerd - Andrew Clegg
Heather
The quackometer: Chiropractors told to take down their web sites - http://shar.es/fCGD (via http://friendfeed.com/alethea)
LOL - Andrew Clegg from twhirl
waiting for them to try to sue themselves out of this one - Mr. Gunn
+1 Mr Gunn - Bill Hooker
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