Arun Bahl

Preparing notes for the revision period over easter, after completing the #MB1031 poster assessment and the physiology practical write up (#BS1006). Starting the new assessment in #MB1005 on Diabetes, I will be looking at the genetics of the disorder. Whilst keeping up with the work in #MB1004, nice work load for next week. - Arun Bahl

Woah seems like you have quite a bit to do Arun.. Us Biological Science students seem to have so little work compared to you lots! - Neelam Dave

Its nice to know that you like sharing your basic revision routines, approx 6weeks before the start of the exam period and the heat is on! - Mayank Patel from iPhone

Productive start to the semester. - Arun Bahl

Its interesting to know that your interests lie in module content that is unfamiliar. But I also strongly believe that as well as learning new material is excellent, aquiring a broader insight on known knowledge is more rewarding... - Mayank Patel from iPhone

I'm all for a good competition of any sort, but please keep social arrangements (and challenges!) on facebook :-) - Dr Jo Badge

Hows your chemistry revision been so far? - Daanyal Mayet

Good luck BTW. - Daanyal Mayet

2 pm tomorrow - Sha Tim Wai

Thank you - Arun Bahl

This article however concentrates on Werner's syndrome rather than Blooms - Arun Bahl

Thanks Arun, i'm doing the same topic, i'm finding the genetics of it quite hard though, and i need to make sure i fully understand everything so i can explain it convincingly on Friday! - Sami Kimyongur

great to know that youve started review of your assessed topic, looks like the presentation will be worth the watch!...good luck - Mayank Patel

This article shows the effects of Bloom Syndrome (BS) which my current presentation is on in #MB1030. The article shows the cause and possible conclusions of the syndrome on a molecular level, also the large reference of the bloom helicase (which is the protein which has been mutated) as a "caretaker tumor supressor". Therefore there is a very plausible link to the onset of cancer with patients who have the condition, due to the mutation of the tumor suppressor gene to effectively an oncogene. The article also relates to #BS1015 whereby the knowledge from previous lectures on mutations of DNA base sequences has resulted in vast variation to the proteins produced. This example concluding in very different functionalities of the two proteins. - Arun Bahl

wow the article seems to summarise the syndrome pretty well. I ve bookmarked it using delicious.com, i will share some related articles soon as well. thanks for this one. - Syeda Maham Batool

whats delicious.com? Yer this article was really useful! - Arun Bahl

Bloom's and Werner's syndrome is my presentation topic in #MB1030, this article depicts the nature of the disorder and goes on to investigate whether the properties of WRN and BLM affect the annealing of DNA. The discovery of the regulation of these properties could have dramatic effects when treating the syndrome, and possibly the prone onset of cancer which comes with the syndrome. Unfortunately the results show that the "undwinding activities are significantly stronger than previously believed". Therefore still significant work must be done to find how pharmaceutical companies can manufacture medication to combat the effects of the syndrome. - Arun Bahl

This is a very informative report. - Daanyal Mayet

another helpful article for the presentation ! keep it up Arun - Syeda Maham Batool

i have got the same topic for my presentation. feel free to share any useful links :) - Syeda Maham Batool

Its good to know that even those with very difficult, yet interesting topics for the assessed talks are willing not to let the complexity of their talk come in the way of achieving a good mark!...great work arun and syeda, many individuals I know with this specific topic are finding it extremely difficult, and have unfortunately given up all hope of presenting it with the same confidence...its good to know that my friends are always willing and able to overcome these challenges!! - Mayank Patel

Another feed related to the presentation in #MB1030, this time however the relationship is based solely on the link between epigenetics and cancer. "Too little methylation across the genome and too much methylation in the CpG islands can cause problems" taken from the origanl source in The Scientist. The Scientist depicts the original misconception about the link between cancer and epigenetics, however delves further into the newer research commenting on how the tumour supressor genes may be altered. - Arun Bahl

great research acquired arun, I read the article very interesting I must say. Keep up the feeds, I myself am performing soem research on 'sex in the brain' for this module assignment..its more difficult than it sounds I must add... - Mayank Patel

(for #MB1030) - Arun Bahl

The title is "What role is genomics playing in cancer medicine?" - Dr Chris Willmott

I am presenting an article, in #BS1030, from the scientist about epigenetics, this article however correlates to the article found in the scientist. The theory that the environment has an influence on genomics, also how mediators can affect the hereditary material in future generations. Thus allowing the phrase "phenotype" to mean more than just the typical "environmental influence" which was taught throughout a level. Instead this expands on how the environment effects the genotype to produce the phenotype through the influence of epigenetics. - Arun Bahl

I meant #MB1030 for the #BS1010 shall we book a room? - Arun Bahl

The article offers a more general reading background into the functionality of ribosomes, which is required for #BS1015 - Arun Bahl

This video does simplify translation and it's easy to understand! Nice video Arun! - Neelam Dave

ive got to say great video arun...especially for those who dont quite understand translation!...i found it very useful, great recap to prof cundliffes lectures...keep posting penjour! - Mayank Patel

arun this is a great link thanks, the protein structure fascinates me even now, cant wait for prof. cundliffes lecture tommorrow morning..il cu then till jus keep revising! - Mayank Patel

Im sure as the task asks for the biochemical importance of water...perhaps you do not have to highlight the factors from phtosynthesis and movement in plant cells..ive gt so much and ive nt mentioned ne of it...nevertheless it wont harm you if you add additional info but mite make the essay seem overstretched...its an opinion... - Mayank Patel