Elizabeth Costello - Human Microbiome Development Across Multiple Body Sites in Healthy Infants: Assembly and Re-assembly Following Antibiotic Therapy #ASM2012
Neonatal microbial exposure can protect mice against asthma and colitis. Infant derived microbiota protect mice against lethal infection
- Thomas Sharpton
Antibiotic perturbation in the context of early microbiome development: an ongoing study of healthy mother-infant dyads. Routine baseline sampling of infant microbiomes. Antibiotic exposures.
- Thomas Sharpton
Collect infant fecal, saliva and skin swabs on the same days each month. Also, collect maternal fecal, saliva, skin, vaginal and breast milk samples collected at several postpartum months
- Thomas Sharpton
## Interesting to know how maternal microbiome changes from T3
- Ruchira S. Datta
Applying more or less the same data generation process outlined by Rob
- Thomas Sharpton
@Ruchira I agree! but they are only looking postpartum
- Thomas Sharpton
Summarizing the major phyla that are found in their initial samples across ages and sights. Nothing surprising in her assessment
- Thomas Sharpton
Talking about a few specific individuals. Looking at change in taxonomic composition over time. When solid food is added, diversity profile shifts.
- Thomas Sharpton
Saliva and skin have similar development structures
- Thomas Sharpton
Preliminary findings suggests that antibiotics administered for ear infection has an effect on the taxonomic diversity. Some resilience in the system.
- Thomas Sharpton
Stay tuned... (notes were a bit muted because this is all pre-pub).
- Erick Matsen