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Berci Mesko, MD › Comments

Jean-Claude Bradley
Our paper on Chemistry in Second Life is marked as "Highly Accessed" in Chemistry Central Journal - that's nice to discover http://www.journal.chemistryce...
Nice indeed..... - Graham Steel
That's quick :) - Egon Willighagen
it would be nice if the BMC journals put the number of views right on the paper - like JoVE does - Jean-Claude Bradley
Article level metrics FTW....... - Graham Steel
Graham - do you mean that in the old or new meaning? It could work either way :) http://netforbeginners.about.com/od... - Jean-Claude Bradley
Congrats, Jean-Claude! :) - Berci Mesko, MD
Thanks for the link. I always thought FTW meant "for the world"..... - Graham Steel
Graham - if there ever was an abbreviation subject to miscommunication that would be it :) - Jean-Claude Bradley
Berci Mesko, MD
Question of the day: How do you calculate standard deviation for fold change values?
Is your fold change normally distributed? what do you need the sd for? - Yann Abraham
The question is whether you can calculate standard deviation for fold change values if the groups you compare are not matched. - Berci Mesko, MD
So you are considering the ratio of values derived from 2 unmatched populations, like testing 2 populations with different treatments? In that case I would use an ANOVA rather than working with the ratio... or did I miss something? - Yann Abraham
One group of controls and one group of diseased patients. - Berci Mesko, MD
Berci Mesko, MD
Does anyone know the impact factor of PLoS One?
Does it have one? I thought Thomson refused to calculate IF for it. - Pawel Szczesny
Pawel's right. - Björn Brembs
Thank you, that's what I needed. - Berci Mesko, MD
Berci Mesko, MD
6 invitations left for Google Wave. Now I have to do a QPCR, then will be back and add the last 6 requests.
I would like an invitation. nikosg5 at gmail.com. thank you - Nikos G
I'm sorry, no more left... - Berci Mesko, MD
Berci Mesko, MD
I've got 15 invitations for Google Wave. Anyone?
I d like 1 please, nikolaoshornet at gmail.com - Nikolaos Hornet
Done. - Berci Mesko, MD
Attila Csordas
the figure shows the heart rates of 4 subjects only 1 signal is from a healthy person. Can you tell which it is? http://www.physionet.org/physiot...
It wasn't that easy... - Berci Mesko, MD
Berci Mesko, MD
Kevin, MD On The Future Of The Medical Blogosphere - http://scienceroll.com/2009...
"He talks about why he blogs, what results he has seen and the future of the medical blogosphere." - Berci Mesko, MD from Bookmarklet
Graham Steel
Unfortunately, my Athens does not extend to NPG content :-( "Can web 2.0 reboot clinical trials?" Nature Biotechnology 27, 895 - 902 (2009) doi:10.1038/nbt1009-895 http://www.nature.com/nbt...
email in my profile. Thanks. - Graham Steel
On the way - Colby from email
He shoots, he scores. Thanks, Colby !! - Graham Steel
Graham, is there a chance you could send it to me too? :) - Berci Mesko, MD
No problem, Berci. Will ping you a copy later when I'm back home from work. - Graham Steel
Not sure if you sent it Graham but I shot a copy to Berci just now. - Colby
Berci Mesko, MD
"Experienced librarians might like the redesign less, as advanced searches have not become easier." - Berci Mesko, MD from Bookmarklet
Berci Mesko, MD
Interesting topic, can you point me to the information/slides you have shared or collected so far ? - joergkurtwegner
Here it is: http://scienceroll.com/medicin... but will publish slideshow later. - Berci Mesko, MD
Deepak Singh
Fwd: Any Science 2.0 people who are also Wikipedians? Notability of Timo Hannay being debated. Please chime in! http://en.wikipedia.org/wiki... (via http://friendfeed.com/boudicc...)
They actually really want to downscale WP... Wikipedia-- - Egon Willighagen
If they keep this up there will be nothing about the web on Wikipedia - Cameron Neylon from fftogo
Done. I also added the reference to PhDComics in the article. - Pierre Lindenbaum
@Pierre, please check the comic ID... - Egon Willighagen
Joi Ito is adding material.... the article looks pretty good already to me. Added a "Keep" on the deletion page. - Michael Nielsen
@Egon thanks, fixed - Pierre Lindenbaum
I can understand WP doesn't want to have an article on every John Smith in the world, but these endless notability battles are tedious. If you present at one conference are you notable? If you get one interview? "regarded as an important figure by peers" is not exactly a quantitative metric. Timo has a demonstrable body of work in many venues; that should be enough for notability. I was... more... - Richard Akerman
Just weighed in, it will certainly be kept. - Berci Mesko, MD
Yay - just noted that the wiki entry on Timo is no longer being considered for deletion http://en.wikipedia.org/wiki... Common sense prevailed..... - Graham Steel
w00t - Deepak Singh
Shirley Wu
My first post on the 23andMe blog... SNPwatch: Common Variants May Influence Glaucoma Risk in Individuals of African Descent - http://spittoon.23andme.com/2009...
Cool Shirley. Excellent stuff. My father-in-law is a retina specialist. - Andrew Lang
Likey lot - Deepak Singh
The "news report" style can seem a little dull, but I guess I always have my own blog for less formal stuff... - Shirley Wu from twhirl
I found it very hard blogging for the AWS blog even though it's not quite as formal - Deepak Singh
I always mention the Spittoon blog in all of my presentations that focus on how the public could get closer to personalized medicine or genomics. - Berci Mesko, MD
Berci Mesko, MD
E-Health Europe :: Growth predicted in medical automation - http://www.ehealtheurope.net/news...
"Examples of automated medical technologies given include health monitoring kiosks, automated X-rays, e-learning systems and surgical robots" - Berci Mesko, MD from Bookmarklet
Berci Mesko, MD
Placebos Are Getting More Effective. Drugmakers Are Desperate to Know Why. - http://www.wired.com/medtech...
Placebos Are Getting More Effective. Drugmakers Are Desperate to Know Why.
Very interesting Berci - one of the issues I never understood about drug studies is how do you account for the fact that any drug with a common side effect will tip off the patient that they are definitely getting the real stuff and not a placebo - thus contributing to a higher expectation that it should work to alleviate symptoms. - Jean-Claude Bradley
That's true, but sometimes patients who are getting placebos also have side effects. Another unexplained observation :) - Berci Mesko, MD
Placebos don't have side effects ;) - Clare Dibble
Exactly, that's why it's a strange observation. - Berci Mesko, MD
The placebo might have a small incidence of apparent side effects but if you take something like Lunesta the bad taste in your mouth will give you a definite sign that you have not taken the placebo. - Jean-Claude Bradley
same story with recent stem cell trial - no difference with placebo. People believe in "new magic pill" and get "high" emotionally. - Alexey
Two ScienceBlogs had interesting discussions and comment threads on this article last week: http://scienceblogs.com/whiteco... and http://scienceblogs.com/greglad... - Brian Haugen
Berci Mesko, MD
PeRSSonalized Pregnancy: News and Resources « ScienceRoll - http://scienceroll.com/2009...
PeRSSonalized Pregnancy: News and Resources « ScienceRoll
omg :°) - Valentina*
I hope this omg means you like it. :) - Berci Mesko, MD
Berci Mesko, MD
ICMCC News Page » 5 years ICMCC - Congratulations! - http://articles.icmcc.org/2009...
Thank you!! - Lodewijk Bos
My pleasure! - Berci Mesko, MD
Paulo Nuin
We are pleased to announce that Ricardo Vidal (@rvidal) will be joining our group as a graduate student soon
Not a "graduate liaison"? ;-) - Mr. Gunn
@Mr.Gunn lol - Ricardo Vidal
Congratulations to all concerned. - Bill Hooker
Thanks, Bill. We're really happy that is coming to Kingston. Poor kid will come just before winter, so we hope he stick around for longer, after the first snowstorm :-) - Paulo Nuin
Way cool!!! So how are you going to react when he opens up Mendeley :)? - Deepak Singh
Mendeley is currently block in the lab. He will have to prove capable of circumventing our firewall. - Paulo Nuin
Googling "firewall circumvention for dummies"... ;) - Ricardo Vidal
Awesome! Congrats! - Chris Lasher
Thanks :) - Ricardo Vidal
Wow, how cool. Glad to hear it. - Maureen from iPhone
Congratulations! - Yann Abraham
Now details, we want details... - Neil Saunders
Watch your back Paulo, they're trying to get an insider to remove your top search result for "mendeley review" :P Sounds fun. Good luck Ricardo! - Brian Krueger - LabSpaces
Wow! When great people meet :) - Berci Mesko, MD
Berci Mesko, MD
Gene Sherpas: Personalized Medicine and You: Why DTC Genomics IS Medicine. - http://thegenesherpa.blogspot.com/2009...
No, DTC genomics isn't medicine, and it doesn't matter how many times you insist it is. There remains a fundamental difference between information and the uses to which that information is put. Everyone else on the web seems to understand this. Berci, you provide a valuable service aggregating medicine related articles and you're one of my best filters/sources, but i do with your crank-filter were a little tighter sometimes. - Mr. Gunn
Thank you, Mr. Gunn! Well, sometimes it happens. But I must admit I know Steve Murphy personally and he seriously affected my thoughts on personal genomics. He helped me a lot about how to become a clinical geneticist and in the vast majority of cases, I agree with his opinion. In terms of outcomes or consequences, DTC genomics should be considered medicine. - Berci Mesko, MD
I want to make sure I understand your argument, because I'm sure it must be a little more subtle that what I get from reading his post. Are you saying that because someone might make a medical decision for themselves based on the data returned from somewhere like 23andme, it should be put in the same category as a medical diagnostic test, and regulated by requiring a doctor's order? - Mr. Gunn
I couldn't have said it better. Yes, I think so, and I'm sure Steve thinks pretty the same. DTC is not just playing with fancy results and colorful graphs because people will make medical decisions based on these. And that is dangerous no matter how strongly these companies state these results shouldn't be used for medical decision-making. - Berci Mesko, MD
Berci Mesko, MD
10th interview in one week... Hungarian media likes medicine 2.0...
Congratulations @Berci - BlausenGroup
Thank you! - Berci Mesko, MD
Berci Mesko, MD
I'm looking for the SNP that determines whether eating asparagus makes your urine smelly. Any help?
I've heard that there are "smellers/non-smellers", also "producers/non-producers". Maybe you can sort this out! - Neil Saunders
Thank you, Neil, for the tip! I saw you've already commented on this: http://spittoon.23andme.com/2008... - Berci Mesko, MD
This is the best review I've found so far: http://dmd.aspetjournals.org/cgi... - Neil Saunders
Berci Mesko, MD
"20 ways Surgeons should use Evernote" - Berci Mesko, MD from Bookmarklet
Berci Mesko, MD
After 6 years of hard work, today, I became a medical doctor...
Congrats! - Chris Lasher
Congratulations Berci ! - Nils Reinton
Thank you! :) - Berci Mesko, MD
CONGRATS! - Mary Canady
Congratulations, Dr. Mesko! - Bill Hooker
respect! - Bart
Congratulations Dr. Mesko. You're probably the hardest working person on the planet too :) - Deepak Singh
wonderful! - Jean-Claude Bradley
Congratulations Berci! - Andrew Lang
congrats! - imabonehead
Thank you, guys! Deepak, you tell me this? :) - Berci Mesko, MD
Lol Berci, I think my irony meter shorted out when I read that comment from Deepak. :-) - Bill Hooker
Congrats ! - joergkurtwegner
Nice work, Berci! - Mr. Gunn
Congratulations!! - Shirley Wu
Good for you!!! :-D - Anna Haro
What an accomplishment. Congrats to you. - Derrick
Congrats ! - Khader Shameer
Congrats Berci! - Adarsh
Congratulations! - Yann Abraham
Congrats Man! err, I mean, Doc. :) - अभिषेक(Abhishek) Das
Berci Mesko, MD
PeRSSonalized Medical News: Call for National Versions! « ScienceRoll - http://scienceroll.com/2009...
PeRSSonalized Medical News: Call for National Versions! « ScienceRoll
"PeRSSonalized Medical News: Call for National Versions!" - Berci Mesko, MD from Bookmarklet
Colin Archer
Large-scale identification of genetic design strategies using local search - http://dx.doi.org/10...
The link doesn't work. - Berci Mesko, MD
Works now OK. I guess the RSS feed was in front of the website. - Colin Archer
Jeffrey Leow
im accepting ads on my blog. to be honest, im pretty happy with the monetary gain.
I will open my blog, Scienceroll.com, for advertisements in 2 weeks. Exciting times... - Berci Mesko, MD
Berci Mesko, MD
Online vs Offline:Is Your Boss on Facebook?A girl posted a message about her job. But the boss was also there http://scienceroll.com/2009...
Looks shooped. I can tell by teh pixelz. - Mr. Gunn
Are you sure? It seems to be quite real. - Berci Mesko, MD
Warner Crocker
Oh no. Everyone took Robert Scoble's advice and unfollowed everybody else and now there is no Twitter!
Social network implosion. - George Frink
Daily LOL :) - Berci Mesko, MD
Those spammers could take scoble's advice... - k00pa from iPod
Ha ha! Tha'ts very funny, wish I had thought of that! - Sandra Large
Very good - Leigh Marriner
Berci Mesko, MD
Don’t Forget PubMed Re-Design Online Meeting « Krafty Librarian - http://kraftylibrarian.com/...
I had forgotten about this, Berci. Thanks for the reminder. I'll be attending, online/phone. - Graham Steel
Great, Graham. I hope you will make and share some notes. :) - Berci Mesko, MD
Arse. I got side-tracked writing a comment on the PatientsLikeMe - ALS Forum and missed the first 30 mins of the 45 min event. Someone coughed most of the way through the last bit although David Gillikin came across clearly. Must make contact with him. Let's hope that our Krafty Librarian can provide a less ambiguous summary :-) - Graham Steel
Krafty is also quick. Here's her summary:- http://kraftylibrarian.com/... - Graham Steel
Thank you, Graham, for the link! - Berci Mesko, MD
Berci Mesko, MD
"Now it’s possible to sequence a person’s genome for under 5000$ and the 1000$ aim can become a reality soon" http://scienceroll.com/2007...
That is incredible, I remember a couple years ago it was predicted to happen around 2011, and Church estimated $100 by 2013. Looks like it will happen much faster, thanks for the update. - Colby from PeopleBrowsr
I am very skeptical of the cost. Does it include the cost of consumables, which don't have the same economies of scale. What about people, power and compute? In other words, this is NOT a fully loaded cost - Deepak Singh
You're right, Deepak, this is not the full cost, just the cost of the sequencing itself. - Berci Mesko, MD
As I thought. Would be nice if the folks talking about those numbers were clear about the costs not being fully loaded - Deepak Singh from IM
This is already sounding like TCO arguments over operating systems. Total Cost of Genome Ownership ... I guess companies like 23andMe would also argue that you need to factor in the cost of access to decent analysis tools. A raw string of ATCGs isn't much use to the average punter ... - Andrew Perry
that's one step further down. I am still at the level of a run. Of course, with instruments, storage, downstream computing, etc, this adds up fast. For someone like 23andme, storage costs, analysis tools and web infrastructure will add up quickly - Deepak Singh from IM
Berci Mesko, MD
Just learnt to use an Automated Liquid Handling robot properly. Small steps in a PhD... :)
what brand? - Jean-Claude Bradley
Tecan - Berci Mesko, MD
Used to manage a facility with a Multiprobe II HT. - Paulo Nuin
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