Constantinos Lipsos
Asymmetric cell division: recent developments and their implications for tumour biology - http://www.nature.com/nrm...
I chose to post this article because it is related to my #MB1030 lecture on the beginning of the semester on cancer and on my recent essay on genomics and cancer. This article gives me a better understanding of how cancer begins to develop. According to this article some certain phosphorylation events that occur during cell mitosis may cause the asymmetric segregation of the chromosomes. Also in the asymmetric cell division are involved centrosomes and microtubules. As a result we have stem cells with a different number of chromosomes than the parent cell. This cell will later turn into a cancer cell but the exact mechanism by which it becomes a cancer cell is still unknown. - Constantinos Lipsos