by Jian Xu, Peifeng Ji, Zixia Zhao, Yan Zhang, Jianxin Feng, Jian Wang, Jiongtang Li, Xiaofeng Zhang, Lan Zhao, Guangzan Liu, Peng Xu, Xiaowen Sun Background Single nucleotide polymorphisms (SNPs) have been used as genetic marker for genome-wide association studies in many species. Gene-associated
- Bastian Greshake
by Jian Xu, Peifeng Ji, Zixia Zhao, Yan Zhang, Jianxin Feng, Jian Wang, Jiongtang Li, Xiaofeng Zhang, Lan Zhao, Guangzan Liu, Peng Xu, Xiaowen Sun Background Single nucleotide polymorphisms (SNPs) have been used as genetic marker for genome-wide association studies in many species. Gene-associated
- Bastian Greshake
The New York Times has an article on New York’s suicide cops who are tasked with talking down potential ‘jumpers’. If you want to read something that’ll restore your hope in humanity, give this article ten minutes of your time. In Midtown Manhattan or the financial district, for instance, pedestri
- Bastian Greshake
The New York Times has an article on New York’s suicide cops who are tasked with talking down potential ‘jumpers’. If you want to read something that’ll restore your hope in humanity, give this article ten minutes of your time. In Midtown Manhattan or the financial district, for instance, pedestri
- Bastian Greshake
In August of 1951, a strange epidemic struck the sleepy little town of Pont-Saint-Esprit in France. Over the course of a single day, hundreds of people lost their minds.... Torsten Passie1 , John H. Halpern2,3 , Dirk O. Stichtenoth4 , Hinderk M. Emrich1 . (2008) The Pharmacology of Lysergic Acid Die
- Bastian Greshake
In August of 1951, a strange epidemic struck the sleepy little town of Pont-Saint-Esprit in France. Over the course of a single day, hundreds of people lost their minds.... Torsten Passie1 , John H. Halpern2,3 , Dirk O. Stichtenoth4 , Hinderk M. Emrich1 . (2008) The Pharmacology of Lysergic Acid Die
- Bastian Greshake
The Kissing Sailor, or “The Selective Blindness of Rape Culture” | Crates and Ribbons was posted 9 times. via Top-Links out of the Twitter-timeline of @gedankenstuecke http://gedankenstuecke.de
- Bastian Greshake
The Kissing Sailor, or “The Selective Blindness of Rape Culture” | Crates and Ribbons was posted 9 times. via Top-Links out of the Twitter-timeline of @gedankenstuecke http://gedankenstuecke.de
- Bastian Greshake
Nate Silver, everyone’s favorite statistician made good, just gave an interview where he said he thinks many journal articles should be blog posts. I have been thinking about this same issue for a while now, and I’m not the only one. This is a really interesting post suggesting that although scienti
- Bastian Greshake
Abstracts are summaries — the short paragraph that usually explains the question a study was asking and the answers it found, plus a brief overview of what methods the researchers used. Because most peer-reviewed scientific research papers sit behind big, awkward pay walls, abstracts are often the on
- Bastian Greshake
The Newberry volcano’s caldera. Image: USGS By Liat Clark, Wired UK With reports only recently confirming that fracking is not, as long as its properly regulated, the earthquake-generating terror we thought it was, a US geothermal company has decided it’s a great idea to extract clean energy from
- Bastian Greshake
Abstracts are summaries — the short paragraph that usually explains the question a study was asking and the answers it found, plus a brief overview of what methods the researchers used. Because most peer-reviewed scientific research papers sit behind big, awkward pay walls, abstracts are often the on
- Bastian Greshake
The Newberry volcano’s caldera. Image: USGS By Liat Clark, Wired UK With reports only recently confirming that fracking is not, as long as its properly regulated, the earthquake-generating terror we thought it was, a US geothermal company has decided it’s a great idea to extract clean energy from
- Bastian Greshake
Nate Silver, everyone’s favorite statistician made good, just gave an interview where he said he thinks many journal articles should be blog posts. I have been thinking about this same issue for a while now, and I’m not the only one. This is a really interesting post suggesting that although scienti
- Bastian Greshake
Thirty-two common variants associated with body mass index (BMI) have been identified in genome-wide association studies, explaining ~1.45% of BMI variation in general population cohorts. We performed a genome-wide association study in a sample of young adults enriched for extremely overweight individuals. We aimed to identify new loci associated with BMI and to ascertain whether using an extreme sampling design would identify the variants known to be associated with BMI in general populations.
- Bastian Greshake
Thirty-two common variants associated with body mass index (BMI) have been identified in genome-wide association studies, explaining ~1.45% of BMI variation in general population cohorts. We performed a genome-wide association study in a sample of young adults enriched for extremely overweight individuals. We aimed to identify new loci associated with BMI and to ascertain whether using an extreme sampling design would identify the variants known to be associated with BMI in general populations.
- Bastian Greshake
Peter Visscher and colleagues have recently published a flurry of papers employing a new software package called GCTA to estimate the heritability of traits using GWAS data (GCTA stands for Genome-wide Complex Trait Analysis -- clever acronymity!). The tool, supported (and presumably coded) by Jian Yang is remarkably easy to use, based in part on the familiar PLINK commandline interface. The GCTA Homepage provides an excellent walk-through of the available options.
- Bastian Greshake
«after all, there are seven books claiming that Harry Potter is a wizard, and there aren't very many people who see that as anything but fiction.»
- Bastian Greshake
These results indicate a substantial, but by no means total, contribution of genetics underlying susceptibility to both early-onset and late-onset PD, suggesting that, despite the novel associations discovered here and elsewhere, the majority of the genetic component for Parkinson's disease remains to be discovered.
- Bastian Greshake