#icsb2010 Tony Hey - Data-intensive scientific... - ICSB 2010

"This is known as the suitcase talk" (giving the closing lecture) - Lars Juhl Jensen

Has problems with the PowerPoint presentation - excuses himself that it is a Microsoft problem (Tony is from Microsoft Research) - Lars Juhl Jensen

The Data Deluge, we will create more data over the next five years than we have ever had so far - Lars Juhl Jensen

Attending ICSB 2010: £435. Train ticket to Edinburgh: £58. Windows freezing during Microsoft Research VP's talk: priceless. - Vangelis Simeonidis from iPhone

Free genomes for all! - Neil Swainston from iPhone

Expects sequencing costs to drop to effectively zero and that genomes will be used to predict who will respond to which drugs - Lars Juhl Jensen

Showing large data examples from astronomy and particle physics - too much data and too few scientists to analyze it - Lars Juhl Jensen

Astronomical amounts of data being generated in physics. - Neil Swainston from iPhone

Citizen Science: Galaxy zoo - 200,000 people help classify galaxies - Lars Juhl Jensen

We made it! too bad we missed the ppt blunder... - Ricardo Almeida from Android

Lots of data but how to analyse? Galaxy Zoo - crowd sourcing. - Neil Swainston from iPhone

Plug to crowdsourced science - Pedro Beltrao from Android

Hanny van Arkle's Voorwerp - the bluest galaxy ever discovered (found by a Dutch school teacher among the masses of data) - Lars Juhl Jensen

The fourth research paradigm: 1. experimental science, 2. theoretical science, 3. computational science, and now 4. data-intensive science - Lars Juhl Jensen

Discussing the impact of big data to the way we work in science today and in the future. We need new skils in big data analysis, visualization etc - Pedro Beltrao from Android

(No hypothesis science ? Gasp :) - Pedro Beltrao from Android

Data intensive science. Here's the data, now what is the hypothesis? Doug Kell should write a paper on that. - Neil Swainston from iPhone

Generic problems in data-intensive science: data ingest, managing a petabyte, common schema, how to organize it, how to reorganize it, how to share with others, query and visualization tools, building and exceuting models, integrating data and literature, documenting experiments, and curation and long-term preservation - Lars Juhl Jensen

Ingesting a petabyte is difficult. Sharing it afterwards is even harder - and actually illegal in some countries. - Daniel Jameson from iPhone

One of the big differences between data in particle physics and biological sciences is that the latter has many more different types of data - Lars Juhl Jensen

Computer science has failed to produce the tools that work for biologists - Pedro Beltrao from Android

Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era. http://www.ncbi.nlm.nih.gov/pubmed... - Neil Swainston from iPhone

To be fair, biologists haven't created useful tools for computer scientists either. - Neil Swainston from iPhone

The book "The Fourth Paradigm" is available under a Creative Commons license here: http://research.microsoft.com/en-us... - Lars Juhl Jensen

Cc licensed book: The Fourth Paradigm. Free of charge, PDF and Kindle. - Ricardo Almeida from Android

Wow, mentions the problem of access to papers and open access movement - Pedro Beltrao from Android

Good plug for Open Access - if public money paid it, it ought to be freely available to the public - Lars Juhl Jensen

An e-Science example: machine learning and healthcare - Lars Juhl Jensen

Is there anyone that Doug doesn't know? I bet he's been out for a pint with at least three of the Chilean miners. - Neil Swainston from iPhone

Microsoft Research and HIV. Microsoft researcher formally worked on spam filters. PhyloD.net deciphers evolution of HIV virus. - Neil Swainston from iPhone

Umm.. a weird analogy too long to explain - Pedro Beltrao from Android

Working on understanding environmental and genetic factors responsible for asthma and diabetes (and other diseases) - Lars Juhl Jensen

PhiloD.net - application of machine learning and high performance computing in HIV non-masking epitope discovery. - Ricardo Almeida from Android

Trying to use machine learning to predict which patients require readmission (i.e. who were sent home from the hospital too soon) - Lars Juhl Jensen

PhiloD.net is designed with Microsoft's Azure cloud computing platform. - Ricardo Almeida from Android

using machine learning with patient data to predict readmission - Pedro Beltrao from Android

Healthcare. Machine learning to prevent readmission to intensive care. Based on very simple meta-dataset of patients condition. - Neil Swainston from iPhone

Tools developed for Life Sciences: a formatting scheme for Word? - Vangelis Simeonidis from iPhone

Microsoft support and develop biologist's tools. Plugins for word for marking up with ontology terms. - Daniel Jameson from iPhone

Word add-in for ontology recognition in papers. Good stuff. Word. - Neil Swainston from iPhone

He mustn't have heard of Endnote or Zotero.. - Ricardo Almeida from Android

Describing MS Word plugins for saving documents in PMC XML format and mark-up of ontology terms. Sadly they don't work on OS X. - Lars Juhl Jensen

That's a bit better. Text mining plug in for Word. - Vangelis Simeonidis from iPhone

Also chemistry add-in for Word. CML in the background. Can show name, formula or structure. Quite cool. Sure that the Google Wavers attempted to write a plug-in to do something similar. - Neil Swainston from iPhone

Trident scientific workflow tool looks to be worth a look. Missed the URL though. - Daniel Jameson from iPhone

Slightly underwhelmed so far with all the plug in talk. - Vangelis Simeonidis from iPhone

Plug ins for excel... networks in excel ... scary - Pedro Beltrao from Android

Excel is the curse of all data if you wish to subsequently process is automatically. - Daniel Jameson from iPhone

Should MBF be invited to COMBINE 2011? - Vangelis Simeonidis from iPhone

Actually, chemistry plug-in is FAR more necessary for Excel. Imagine if all crappy Excel data sheets would contain semantic ChEBI identifiers within them? I'd be out of a job... - Neil Swainston from iPhone

.net libraries for biology ...sounds interesting - Pedro Beltrao from Android

(I plan to make a plugin to put Neil out of work ;-) ) - Lars Juhl Jensen

Systems Biology is looking at biological systems. - Daniel Jameson from iPhone

If you cannot wait to have all the Office plug ins: http://atom.microsoft.research.com/bio... - Vangelis Simeonidis from iPhone

Www.cosbi.eu blenX something about language integration - Pedro Beltrao from Android

Supporting both top-down and bottom-up. I fear that this leaves us mere mortals with just middle-out. - Neil Swainston from iPhone

Ethanol or whatever! - Ricardo Almeida from Android

Kind of scatered, talking about different collaborations - Pedro Beltrao from Android

Metabolic Engineering approach doesn't look that impressive. Seen lots if examples of similar work this week. Jesus! They've recreated SBML!! - Neil Swainston from iPhone

.net is all well and good, but we aren't all developing for windows only - infact that's an incredibly bad idea... - Daniel Jameson from iPhone

Here comes the azure plug - Pedro Beltrao from Android

And I thought I was the only person in the world using SmugMug... - Vangelis Simeonidis from iPhone

What's a cloud? There's a definition... - Ricardo Almeida from Android

"many people talk about clouds". eg meteorologists - Vangelis Simeonidis from iPhone

100K to 1MK servers with big cost savings. Container size modules.questions on energy efficiency etc. Half billion for the chicago center. - Pedro Beltrao from Android

Microsoft making cloud computing facilities in Iraq?!? Did I just mishear that? Considering waterproof servers to mitigate the need for expensive buildings. Some centres physically enormous. - Neil Swainston from iPhone

@Neil Swainston: and now you know why you went to war: so that Microsoft can give us cloud computing - Vangelis Simeonidis from iPhone

Different models of cloud computing - platforms and softw as services - Pedro Beltrao from Android

Kind of think that this is the wrong audience for a cloud computing sales pitch. Most of us are still at the "e-mail spreadsheets to each other" level of sophistication. - Neil Swainston from iPhone

PhyloD: statistical tool for dna analysis. It is also a web service through azure - Vangelis Simeonidis from iPhone

Future prospects, semantic computing in the cloud - Pedro Beltrao from Android

Cloud computing makes me nervous: what happens when servers crash? - Vangelis Simeonidis from iPhone

Semantic computing. RDF and OWL namechecked, but speaker is sceptical that these will ever take off on a big scale. - Neil Swainston from iPhone

Prefers an inference approach, which is likely to be more practical realistically. - Neil Swainston from iPhone

Easy to use tools for scientists. Amen to that. - Neil Swainston from iPhone

In summary, it seems that Big Companies see biological data management as a future cash-cow. Likely that most data management will be performed outside of academia in a few years time. - Neil Swainston from iPhone

Not necessarily a bad thing, but highlights the need for geeks like me to focus more on data interpretation than data management. - Neil Swainston from iPhone

Tony Hey finishes with "the cloud WILL be part of your future". Is that a promise or a threat? - Vangelis Simeonidis from iPhone