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Allyson Lister
SIG: DAM and BOSC Joint Session: PSLID, the Protein Subcellular Location Image Database: Subcellular location assignments, annotated image collections, image analysis tools, and generative models of protein distributions, Robert Murphy, Carnegie Mellon
Every software app he describes in this presentation are available on his website and is open source - Allyson Lister
Nice, professional bloggers have arrived at BOSC. Source code available from: http://pslid.cbi.cmu.edu/release... and http://murphylab.web.cmu.edu/softwar... - Brad Chapman
Like the machine learning approach for this. Uses the model as a means to communicate information on distriutions, handles mixtures of distributions. Claims better results / precision than those obtained by human curators. - Oliver Hofmann
If you want to do cell simulations, then you can combine models together. Interesting for things like the virtual cell, as you can model the proteins inside the cell with this. - Allyson Lister
@Brad - you were doing a great job all on your own! :) - Allyson Lister
Pre-annotated image data sets are also available via http://murphylab.web.cmu.edu/data... - Oliver Hofmann
This now leaves me wondering how one goes about storing the locations and trajectories of subcellular structures in a more concise fashion. - Jim Procter
@Jim - is there a common format for movement of cells? I've recently done some work on the Cell Behavior Ontology (http://cbo.compucell3d.org/index...), but don't know if there is an equivalent syntax for it. - Allyson Lister
@Allyson - no clue - I don't think I've come across one but I bet someone is doing it now. The technology seems to be there to deal with these resolutions - I guess its a cell ontology related issue though, too (there's at least one of those for neurons) - Jim Procter