Originally for alignment of capillary sequencing, modified to handle short read data. Uses k-mer hashed genome and Smith-Waterman. Can handle paired end reads. Accurately maps a high percentage of reads on simulated data. Has pipeline for calling SNPs, indels - also tested on simulated data. I/O is all text based. Outputs FASTQ, CIGAR, SAM. Can pre-calculate genome hash and can be tuned to run with relatively limited memory requirements. Free to use.
- Cass Johnston