validation: ortholog lethal ration: the proportion of yeast genes whose orthologs in another species, specifically, C. elegans, are lethal - Ruchira S. Datta

hypothesis about ortholog lethal ratio: nonlethal genes in lethal complexes > nonlethal genes in nonlethal complexes - Ruchira S. Datta

hypergeometric enrichment test was not significantly different, but the Bayesian network model was validated. they think this is because the hypergeometric test produced many false positives - Ruchira S. Datta

gene lethality is more conserved at the module level - Ruchira S. Datta

use module-based mapping to transfer phenotypic mapping across species, rather than gene-based - Ruchira S. Datta