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The #BS1006 practical this afternoon was on heart electrophysiology. This graph shows the ECG trace very clearly and the different components that make up the cardiac electrical cycle. There are even indications of where to begin and end the PQRST intervals for their measurements.
Roisin Thomas, Gagandeep Bawa, Shayna Jo Franzetti and 2 other people liked this
I used this graph before and it really help me understand about the different sections of ECG.
- Kashif Qamar
This is explained so nicely!
- Aisha Siddiqui
this was really helpful for writing-up the practical in 'BS1006. it explains p.t and qrs complex really well. thanks!
- Gagandeep Bawa
I had never really thought of our postures as being controlled through reflexes. The #BS1006 lecture today taught me a lot about the wonders of the human body! And the little hairs in the ear that let us know when we move our head - it's a well coordinated and complex nervous system.
Tutorial 23.2 The Hardy-Weinberg Equilibrium - http://bcs.whfreeman.com/thelife...
Bejal Mandalia, Shayna Jo Franzetti and Kashif Qamar liked this
#MB1005 This explains why the dominant alleles in a population do not always filter out the recessive alleles unless there is selective pressure to do so. There is a nice graphical illustration of the effect of changing allele frequencies on the proportions of homozygous and heterozygous genotypes.
- Jennifer Kwan
from Bookmarklet
When you just look at it the Hardy-Weinberg concept seems to be very difficult. But if you arrange the data in a form of finding the allele frequency first and than performing the chi-squared test to determine the equilibrium, it becomes simple. The examples we did about Hardy-Weinberg eqm in tutorial helped me alot in understand the reasoning behind using this method.
- Kashif Qamar
it was a very productive tutorial and i hear that questions in the exam will be fairly similar! so it's a good job we attended and gained something from the tutorial!
- Neel
This was my best tutorial by far, it was clear and easy, just how i like it.
- Bejal Mandalia
Yeah, in the lecture today we were told how most of the questions in the exam will revolve around the problem-solving nature of the questions in the tutorials. In that case it's a lot more focussed on human inheritance of disease and the meiosis aspects of the module.
- Jennifer Kwan
from iPhone
The #BS1011 is ending and am just reflecting on what we've been doing for Friendfeed so far. It's a neat tool, very handy for sharing information with one another...
...such as webpages, news, or anything interesting at all! I've found the experience enriching, learning from others, sharing opinions, and knowing I'm not alone with any difficulties I encounter. A tool like Feiendfeed will surely be invaluable in our future careers when it comes to networking.
- Jennifer Kwan
from iPhone
The scientific report in #MB1031 is demanding a lot more thought and deduction than the previous draft we did. This time you really have to integrate knowledge from different areas of the taught modules and figure out what's going on. I've still got a lot of "why?" in my report.
I agree Jennifer .... there just seems to be too much information relevant to this report.
- Kashif Qamar
You shouldn't be integrating too much info from other modules - remember you are introducing THIS experiment and discussing what IT shows, not going into details beyond the scope of the study
- Dr Chris Willmott
Hmmm...ok, so focus more on the experiment carried out and what IT means rather than how everything else works.
- Jennifer Kwan
BBC NEWS | Health | 'Gene cure' for colour blindness - http://news.bbc.co.uk/2...
Shayna Jo Franzetti, Jassica and Kashif Qamar liked this
Well, if you ever needed proof the work we do is real and relevant science, here's an extension of the #MB1031 report we're doing on colour blindness. Scientists have isolated the gene required to distinguish red and green colours and through gene therapy have given colour sight back to squirrel monkeys!
- Jennifer Kwan
from Bookmarklet
Hmmm, I'm still a little fuzzy about correlation and when it's suitable to be used. Trouble arose when I did the questions on plotting the scatter graphs and got a straight line.
Ashley liked this
In #BS1006 we learnt about the role of intracellular Ca2+ binding to calmodulin to create smooth muscle contractions. Below is a diagram of what happens during relaxation, and how Ca2+ is pumped back out of the cytoplasm of the cell.
Kashif Qamar and Tom Hutchinson liked this
A short #BS1006 practical, but I like experiments when you actually do them on yourself! We did so many calculations, now I just need to run through the why's and how's, and the significance of the calculated value we got for efficiency. Well pedalled, Joe!!
The #MB1031 poster session was a new experience, but the afternoon went well, and it was nice to see so many bright and colourful posters up! Ah, at least we got through the questioning.
Kashif Qamar liked this
Enjoyed the pressure of the moment when the examiners ask questions and you come up with things (relevant of course) which you didn't remember reading about.
- Kashif Qamar
Really ;) Well, there's nothing like pressure to poke answers out of you then.
- Jennifer Kwan
Anatomy & Physiology: Cardiac Muscle Contraction - CliffsNotes - http://www.cliffsnotes.com/study_g...
Roisin Thomas, Gagandeep Bawa and Kashif Qamar liked this
A few quick notes on cardiac muscle depolarization for #BS1006. Although the conduction of action potentials and generation of tension is roughly the same as in skeletal muscle, the distinguishing shape of the cardiac action potential plateau occurs due to long Ca2+ entry and very little K+ exit from the cell.
- Jennifer Kwan
from Bookmarklet
this is actually quite useful as it explains the events happening when a cardiac muscle contracts in a note form. this will be useful for the #BS1006 exam in summer. it also compares between the action potentials of cardiac and skeleton muscle and the fact that cardiac muscle has a longer refractory period than skeleton muscle. thanks!
- Gagandeep Bawa
Animation: Mechanism of Steroid Hormone Action (Quiz 1) - http://highered.mcgraw-hill.com/sites...
#MB1004 - A review of the role of intracellular receptors and how they affect DNA transcription. I needed a look back at how they work and where the ligand-receptor complex binds.
- Jennifer Kwan
from Bookmarklet
#BS1006 - This image really helped in visualising the muscle fibres and t-tubule arrangement in 3D. You can see the connection of t-tubule to extracellular environment.
Kashif Qamar liked this
You need to click on the image to see the enlarged version!!
- Jennifer Kwan
The role of the T-tubules is to ensure that the calcium (and nutrients) are reached to the cells further in the filament allowing all the cells to contract at the same time.
- Kashif Qamar
True, but I had such a hard time figuring out what it meant by "t-tubles being connected to the outside environment".
- Jennifer Kwan
YouTube - Breakdown Of ATP & Cross Bridge Movement During Muscle Contraction - http://www.youtube.com/watch...
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Kashif Qamar and Jalal Freedom liked this
#BS1006 - Always good to see things in action, here's a movie on cross-bridge cycling and how the binding of calcium to troponin affects the position of tropomyosin.
- Jennifer Kwan
from Bookmarklet
One of the most important thing that I have learnt from this video is that binding of myosin to actin is due to binding sites being revealed by calcium ions attaching to troponin. The other thing is that the binding of ATP to the myosin head results in the detachment of the bond between myosin and actin. Furthermore hydrolysis of ATP returns myosin head to upright position so that the stroke can begin again.
- Kashif Qamar
Looking over the #BS1006 lectures now, trying to figure out the role of Ca and how it is different for skeletal and cardiac muscle. At the moment it's a little difficult to appreciate, but perhaps by integrating with the material from previous lectures I can get a better overview.
Whoa, the earliest I've ever finished my #BS1011 assignment. Pretty ok this week, as we've come across chi-square test before in the genetics experiments. Puzzling out degrees of freedoms is more tricky.
Mechanism of Action: Hormones with Intracellular Receptors - http://www.vivo.colostate.edu/hbooks...
Kashif Qamar liked this
This expands a bit on the intracellular receptors we learnt in #MB1004. It is easy to follow how hormone binding allows these intracellular receptors to bind to DNA and affect transcription.
- Jennifer Kwan
from Bookmarklet
Thinking over the mechanisms of muscle contractions after the #BS1006 lecture just now. Unbelievable how much work needs to be done to get my fingers typing at this keyboard: the many APs fired, their summation, and the many cross-bridge cycles being done. Simply unfathomable!
petronila and Kashif Qamar liked this
and to think we sometimes take this for granted...so if there is a malfunction in this mechanism...how hard life would be.....just amazing=)
- petronila
Just to clarify the #BS1011, for future experiments we need to tabulate data as a column, test for normal distribution, decide on null hypothesis, decide which t-test, and test variance, then calculate result of t-test? All this to look for similarity of two datasets!
Before you run any statistical tests, you need to explore the data, so you need to test for normal distribution and decide on a null hypothesis. Which test you run after that depends on what you are trying to achieve.
- Dr Alan Cann
So that means all statistical tests are based on the fact the data are normally distributed? If they are skewed what can we do?
- Jennifer Kwan
Well done #MB1005 group people! Got through the presentation :)
It was painful journey :D
- Kashif Qamar
Good idea having the tutor meetings yesterday for #MB1031. I feel more confident now writing a report than before when we'd never done one. I got to clarify what is vital and not necessary in the introduction, and how detailed each section should be, as well as what tables should be included in results.
Sharon Yim, Tom Hutchinson, Dr Chris Willmott and Chi-Feng Lin, Jerry liked this
1 to 1 appointment with tutor is always useful. :)
- Sharon Yim
Felt like the second #MB1004 tutorial whooshed right past my head. Anatomy? G protein cascades? Yikes, when you learn about a receptor there's a lot more than just neurones. You've got to know about muscle contractions, cardiac muscle, regulation etc.
Ashley liked this
I was totally lost myself, made me wonder if I'd totally forgotten a lecture or two :( I'm still confused as to whether we ever learnt about these things or if we were expected to do background reading :( Glad to know im wasnt alone lol
- Ashley
our tutor kept saying that we'll hear more about this stuff in later lectures... great....
- Heba Mohamad
Tutorial 13.1 The lac Operon - http://bcs.whfreeman.com/thelife...
Kashif Qamar liked this
#MB1005 This movie illustrates how the role of lactose in preventing the lac repressor from binding, and allowing the production of mRNA, occurs if lac repressor is always being made.
- Jennifer Kwan
from Bookmarklet
Ohhhh, we've reached the last of the #MB1005 practicals. I'll miss them. I had the most fun during these sessions than for other subjects. It was interesting, and one of the best organised courses. Should I pick this next year?
Heba Mohamad, Ashley and Sharon Yim liked this
True ...
- Kashif Qamar
If you like it, why not take it? and by the way, where can we see which modules can we chose from for the next year? I mean where in backboard?
- Sharon Yim
Sharon, you can see the different modules to choose from on the blackboard website. Click on the tab that says "Biological Sciences School Office," and then the "degree programmes tab.". From there, click on "Module Selection Handbook." Good luck!
- Aisha Siddiqui
Yeah, will definitely consider. And wait to see if there will be clashes in picking this module next year.
- Jennifer Kwan
#BS1009 is very interesting because it's a subject that's completely new and microbes are not usually thought of as being "of use" to us. But does anyone find the names and terminology a problem?
A look over the lecture notes and you realise the length and complexity of names. I find it hard to remember such terms when I don't really understand them eg. ladderane lipids. I suppose it's like learning a new language.
- Jennifer Kwan
It's true, there are a lot of names to learn. How else could it be done?
- Dr Alan Cann
I think it's the Latin name for each species that throws me off. And am trying to find a way of remembering which are an/aerobes, facultative, obligate, photo/chemotrophic or auto-heterotrophic.
- Jennifer Kwan
Huge problem for me ... IT's tooooooo difficult to memorise every single one..
- Samuel Lee
Especially the taxonomy part... Do we have to learn every single one ??????!!!!!
- Samuel Lee
No, at least I hope not. Usually what is needed is the "overview". Having said that, knowing some species will be handy for giving examples.
- Jennifer Kwan
You would be amazed by how much the average human brain can memorise. It's all about repetitive reading the words over a period of days. It is called memory consolidation but the hard bit is not can you do it, but rather can you convince yourself you can do it. Mind over matter, believing is everything. :-)
- Mohamed Isse
Neuron Basics - http://www.mindcreators.com/NeuronB...
Aisha Siddiqui liked this
#MB1004 - I like the explanation of the action potential in this site. The graph shows when Na and K channels open and close and why there is hyperpolarization after depolarization. The little nugget at the bottom on stimulus strength and frequency of firing is very useful.
- Jennifer Kwan
from Bookmarklet
graphs are a little more detailed in the link than they are in our lecture notes so thanks for sharing! =)
- Aisha Siddiqui
No problem! :)
- Jennifer Kwan
What Is a Bacterial Endospore?: The Resistant Structures of Bacillus and Clostridium Bacteria - http://bacteriology.suite101.com/article...
#BS1009 This explains the functions of endospores nicely, and how they arise as well as the bacterial species that are able to do so.
- Jennifer Kwan
from Bookmarklet
We've had the last of our #BS1009 practicals. Now there's all those questions to answer about microorganisms! But, overall though, I have enjoyed the practicals. There was a lot to do, but I had never grown bacteria before and thought it amazing to identify such tiny organisms.
Also, one thing that really hits home, is the vast amount of bacteria all around us, if those agar plates of cheek, hand-washing and botted water are anything to go by.
- Jennifer Kwan
#MB1031 So, either I need more time to write that essay down, stop drawing, or get a new handwriting. Anyone with legible handwriting and can write fast?
The #MB1004 session yesterday was very informative. Thank goodness we went over the questions. Apparently there's a lot of factors to consider in determining the opening and closing of ion channels. Nerve conduction isn't as simple as inflow and outflow of Na and K.
agree with you totally. Also some calculations need to be done for one or two questions which I didn't experct.
- Chi-Feng Lin, Jerry
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