All of us DM tweeps are compiling a list of DM-based web 2.0 businesses that we're aware of - we'll get back to you soon :) - Nathaniel Payne

Cool - btw, I'm not trying to bash Des Moines - just curious what web 2.0 is there. I have gotten a lot of response about Des Moines. I'm excited to hear! - Jesse Stay from twhirl

No worries - I understood that you were just curious. There's currently a lot of entrepreneurial energy here - co-working, jelly, tweetups, web apps - all are really popular and gaining momentum within the overall community. We're just trying to take a look and see what products have actually come out of all that energy so far. - Nathaniel Payne

48Web is a pretty awesome Web 2.0 business (yea it's my comp... couldn't help it ) - andy brudtkuhl

and we got Google and Microsoft data centers!!!!! - andy brudtkuhl

SmartyPig - andy brudtkuhl

Chris Pirillo is from Des Moines - so we get to count anything he does right? - andy brudtkuhl

The guy who developed jabber/XMPP is from Iowa (not DM, but close). - Nathaniel Payne