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Kochlab

Kochlab

A room for public Kochlab discussions. As of creation in April 2009, I'm not really sure how we will use it. I have in mind posting links to journal articles and commenting on them. Current lab members, alumni, and really anyone welcome!
Blog
Steve Koch
Submitted CAREER proposal & posted to Scribd: http://www.scribd.com/doc... Open proposal for an open science project!
Thank you to everyone who helped and encouraged on this and offered future support! Among many things, one thing I'm a bit embarrassed about is the lack of details in the "broader impacts" and open science parts of the proposal. Definitely it needs more planning and better writing, and the panelists are going to point that out. Hopefully you all understand that it's a product of spending all my time trying to make the research parts as good as I could. - Steve Koch
good luck Steve! - Jean-Claude Bradley
A small step for a team, but a giant leap for #science . - Daniel Mietchen
Thanks everyone! I sort of dropped off the map after submitting the proposal. One of my most successful attempts at actually vacating during a vacation. - Steve Koch
Bummer! Just found out tonight that the proposal was not funded. I have done one read-through of the reviews. First of all, I am once again amazed at the time and effort the reviewers put into reviewing my proposal. There were 6 reviewers in total and they all had a page or more of feedback. And they all pretty much agreed on the main points: (a) interesting proposal that is worth... more... - Steve Koch
Thank you Jean-Claude, Andy, Cameron, and Drew for the Open Science support letters! I am sure that was key to the very positive reviews for Open Science. Thank you to everyone else on friendfeeed who supports me and our other lab members. We now have 7 months to obtain the preliminary data and get a couple publications, and indeed we are now poised to do so. I am confident the lab members can do this, and by eliminating (b) and (c) above, all signs point towards this being a very strong proposal next time. - Steve Koch
well done all 'round! next time you'll knock 'em dead. - D0r0th34
for the CAREER third time is often the charm - good luck for next round - Jean-Claude Bradley
Thanks, Jean-Claude and Dorothea. The CAREER "3rd time's a charm" effect is part of the reason I submitted without strong preliminary data. (But I also thought we'd be able to generate the data in time for the 2nd submission. Now, though, I'm SURE we can before July :) ) - Steve Koch
After thinking about it for a couple days now, I am still very happy that they viewed the open science so positively. I think that's a big deal. - Steve Koch
absolutely Steve - very good feedback about OS being a positive to the funders - Jean-Claude Bradley
Steve, this looks really really promising. If you can come up with interesting data for the next resubmit, I think you have a great chance to get funded. Congratulations! - Bill Hooker
Thanks, Bill! - Steve Koch
Steve Koch
Graham Steel's fantastic open science remix of photo from Cameron's visit - http://www.flickr.com/photos...
Graham Steel's fantastic open science remix of photo from Cameron's visit
Steve Koch
Cameron visited our lab today! Here's a photo of Cameron discussing the tweezers with Anthony. I'm doing my best to suck my gut in.
2009 Cameron Neylon Visit.jpg
Was an awesome day. Thank you so much for traveling and spending time with us today, Cameron! I learned a lot about science and means for carrying out open science. I'm energized about what seems like a very nice future protein-DNA collaboration. And I'm also energized about trying to implement some of the LaBlog and Google wave things you demoed for us. - Steve Koch
I agree it was a great visit. I enjoyed showing you the version of the $100 spectrometer I'm working on and all the great conversation. I hope KochLab can start a collaboration with our friends across the pond. - Andy Maloney from iPhone
I think I'm going to put some nuggets of information from today onto this thread. Here is a link to the Neylon, Ward, Towrie, and Parker Tus-Ter single-molecule proposal (linked in Cameron's open notebook; see PDF at the bottom): http://blogs.chem.soton.ac.uk/sortase... I think that the system they are studying fits... more... - Steve Koch
I started learning more acronyms having to do with open and linked data. RDF = Resource Description Framework http://en.wikipedia.org/wiki... There was some other acronym that I can't remember or find that Cameron was suggesting as a way of bundling an entire open data set of arbitrary format...lots of vowels, something like OAI... "open access...? NOTE... more... - Steve Koch
Cameron showed us some of the robots he and others have programmed for Google Wave. I learned that it's not crazily complicated to write a robot, and that you can use Google App Engine (http://code.google.com/appengi...) to host your code and run the robot. It currently runs Python and now Java. I still don't understand how it connects with Wave, but it solves a mystery to me of... more... - Steve Koch
(Coincidentally (or maybe not), right after waving with Cameron, Google Wave gave me my 20 invites to send out. Let me know if you need one!) - Steve Koch
I'm sure Cameron and others have already said this in their many fantastic presentations and blog posts about wave. But I was happy to hear Cameron agree with my thinking that google wave + robots would be a very good way of handling data analysis workflows. When we process unzipping data, there are a few layers of software involved. I imagine each software application being run in the... more... - Steve Koch
Cameron's current LaBLog at Rutherford can be found here: http://biolab.isis.rl.ac.uk/cameron... Hopefully I'll be able to get access to this to see the edit features (I "requested" an account by logging in with my yahoo openid). I had previously been impressed by the notebook, but today was really wowed when I saw him edit a new entry. The particular things was the ability to... more... - Steve Koch
+1 for a Wave invite, please (pmiller@liv.ac.uk). - Peter Miller
That's wonderful that Cameron visited your lab Steve! For all the usefulness of communication technologies nothing can replace a productive meatspace interaction. - Jean-Claude Bradley
I had a great time - meeting and talking with Koch and the team. Lots of very cool stuff going on and lots of ideas that just seemed to bubble out of it. The meatspace interaction is really important but having that bit of background about what was going on and the context and trust built up here on Friendfeed amongst other places makes the whole discussion a lot quicker and more interesting. - Cameron Neylon
Agree -- pre-meeting definitely made the in-person meeting very quick to start off. & @Peter Miller, sent the invite - Steve Koch
Sounds like a fun (and productive!) day - thanks for sharing it with us, Steve. Also, I would appreciate a Wave invite (if you have any left!) - thanks! tom.tullius@gmail.com - Tom Tullius
I hope to see some cool pics from this meet-up on Flickr :) Science builds upon Science especially in terms of ONS !! http://farm4.static.flickr.com/3358... - Graham Steel
@Tom sent invite (fyi it takes several days to arrive) @Graham I think this is the only picture they got, unfortunately! - Steve Koch
@Steve, Auch well. Best I can do with this 20.kB image is to B&W it, with a bit of res. conf.:- http://farm3.static.flickr.com/2620... - Graham Steel
@Graham, I think I'm missing something. Is there a whole slew of cool open science photos on Flickr somewhere? - Steve Koch
@Steve - I don't think there is..... yet. I take that back. Starter for 10 with http://farm4.static.flickr.com/3089... - Graham Steel
Small number of people use the tags openscience - http://www.flickr.com/photos... and science2.0 - http://www.flickr.com/photos.... - Neil Saunders
Thanks for wave, Steve - Peter Miller
Thanks, Steve - Tom Tullius from iPod
A few comments back, I was simply looking through this filter http://search.creativecommons.org/... with open science - At worst, some really cool Flickr/CC images for future usage for anyone. - Graham Steel
It occurs to me that in virtually every photo of me online I'm wearing the same jacket and same shirt. Typical academic... - Cameron Neylon
Cameron let me in on the mystery acronym: OAI-ORE "Open Archives Initiative" "Object Reuse and Exchange." http://www.openarchives.org/ore... - Steve Koch
For images there are the ONS logos created by Andy Lang and Shirley Wu http://onsclaims.wikispaces.com/ - Jean-Claude Bradley
Steve Koch
DSpace: University of New Mexico's institutional repository - https://repository.unm.edu/dspace...
Steve Koch
Fwd: Steven Congrats to kochlab member Anthony for passing Candidacy Exam today! (via http://friendfeed.com/steveko...)
Steve Koch
The organizers of the 2011 Biophysical Society Annual Meeting have sent out a request for suggestions for symposia. All in my lab agree that an "open science" or "e-science" symposium would be a great suggestion. I personally think it'd be one of my favorite sessions at the meeting. What do you all think?
The meeting is in Baltimore, MD, USA, March 5-9, 2011. - Steve Koch
There're usually over 6,000 attendees, I believe. So, I think it'd be a great way to spread the word about whatever the cutting edge happens to be 18 months from now. - Steve Koch
To make a suggestion, I'd need to know: (a) symposium title, (b) 100 word description of symposium, and (c) 2-4 speakers who'd I'd recommend. - Steve Koch
I think (a) is important because it defines the topic w/ keywords. "open science?" "e-science?" "science 2.0?" "practical examples of open science?" - Steve Koch
I think (b) is important but can be drafted later. - Steve Koch
I think (c) is important, because it'd probably be best for speakers who'd want to attend the meeting anyway. Or who'd like to meet each other in Baltimore. Or perhaps people who'd incite a riot. Right? I don't know really, I've never organized a symposia. Tough to limit to only 4 I'd like to hear speak! - Steve Koch
The deadline for suggestions is October 13, 2009. Looking forward to hearing any opinions on this. I know that there are already fantastic meetings to discuss open science. I think the difference here is that the audience would be people who may not know anything about the future of science. And thus a big impact could be made within a couple hour symposium. With this in mind, I think a... more... - Steve Koch
Some people I would like to hear from at a symposium include, Jean-Claude Bradley, Cameron Neylon, and Michael Nielsen. Of course this is just the beginning of a very long list that I will think more about. - Andy Maloney
Thanks, Andy & that's a great list. I also just realized that it would be great to have a whole slew of posters that discussed implementations of open science. Grouped into one session would be great, but I'm not yet familiar with how they organize them. Seems possible, though. For those of you who don't know, the Biophysical Society poster sessions are great (except for one deficiency of not having beer). They go over four days and have 500+ posters at each session. - Steve Koch
The schedule for symposia at the upcoming 2010 meeting can be found here: http://www.biophysics.org/2010mee... Note most are focused on specific science topics. And the prior 2009 meeting is here: http://www.biophysics.org/2009mee... - Steve Koch
Steve - great idea! I would very much like to attend and present. I think Science 2.0 would capture more than Open Science. - Jean-Claude Bradley
brilliant idea! John Wilbanks ought to be on the list, if you can get him. Possibly also Sayeed Choudhury, Michael Witt, D. Scott Brandt. - D0r0th34
hey, if it's in b-more i might even be able to wander in. Sayeed probably could too - but he does a lot more with the Astro stuff right? (embarrassing that I know less about what JHU does than people across the country do :( ) - Christina Pikas
Thanks everyone! I'm definitely going to send in a suggestion. I've drafted a Google Doc here: http://docs.google.com/Doc... I'd love any input or suggestions! - Steve Koch
Have finished version / going to submit later tonight. Thank you again everyone! - Steve Koch
Submitted! Survey Monkey form was a bit primitive, so I couldn't submit all the suggestions from everyone, but I think I'll be able to do that later. I suggested me as non-speaking chair, and then had 3 slots left. I decided to list Jean-Claude; Michael-Nielsen; and Christina Pikas. - Steve Koch
I look forward to it Steve! - Jean-Claude Bradley
Sounds great! - Christina Pikas from iPhone
Steve Koch
Larry Herskowitz of KochLab passed candidacy exam this morning. Congrats, Larry, you did a great job!
Steve Koch
eResearch Lecture at U. New Meico. Malcolm Atkinson (Edinburgh, http://www.nesc.ac.uk/nesc...) & David De Roure (Southampton, http://www.soton.ac.uk/~dder/)
"open middleware something or other-UK" http://www.omii.ac.uk/ - Steve Koch
De Roure describes Taverna as a "ramp" into e-science: "The Taverna Workbench provides a desktop authoring environment and enactment engine for scientific workflows. The myExperiment social web site supports finding and sharing of workflows and has special support for Taverna workflows. The Taverna workbench, myExperiment and associated components are developed and maintained by the myGrid team, in collaboration with the open source community. " http://taverna.sourceforge.net/ - Steve Koch
Talk going very long, bummer that I have to leave for another important meeting - Steve Koch
I like this workflow stuff--need to learn more. - Steve Koch
myexperiment look into this again http://www.myexperiment.org/ - Steve Koch
Steve Koch
THE OSMOTIC PRESSURE OF CONCENTRATED SOLUTIONS, AND THE LAWS OF THE PERFECT SOLUTION. - http://www.citeulike.org/user... (via http://friendfeed.com/steveko...)
This is a fantastic paper from 1908 that discusses osmotic pressure of concentrated solutions and how Raoult's law leads to correct predictions for actual ideal solutions. Incredibly easy paper to read. - Steve Koch
Steve Koch
Fwd: 2009 September Kinesin Talk at UNM Chemistry - http://www.slideshare.net/skoch3... (via http://friendfeed.com/steveko...)
2009 September Kinesin Talk at UNM Chemistry
Steve Koch
After working hard for like 28+ days in a row, Larry (grad in the lab) is taking a trip to Denver to watch his Rockies battle the Giants. I demand two Rockies victories, he deserves it. Furthermore, I request two Dodgers losses.
During that time period, he wrote TWO really nice software applications: one a stochastic simulation of kinesin walking that will be essential for interpreting ours (and others') data; the other a very cool program to track rotating microtubules in a specialized gliding assay. You can see his tutorial for the latter here: http://www.youtube.com/watch... - Steve Koch
Awesome win for the Rockies tonight! Let's make it another tomorrow for 3 games up in the WC - Steve Koch
Steve Koch
Good news! Looks like our computer whiz Caleb is going to be doing research for credit again this semester. Last semester he did a bunch of cool things for OWW. I'm thinking that he'll have a lot of success with open science tech innovations this semester too.
Steve Koch
From Hope Leman, really cool resource Fwd: "This is a rather useful resource I just came across via Biocrowd molecularmovies.org http://www.molecularmovies.com/index... The one on apoptosis is quite good. (via http://friendfeed.com/hleman...)" KochLab, checkout: http://www.molecularmovies.com/showcas... and...
Steve Koch
If you're interested in Biophysical Society Annual Meeting 2010 #BPS2010 in San Francisco, I created a FF room http://friendfeed.com/biophys...
Steve Koch
Fwd: Larry Herskowitz, Andy Maloney at #INCBN poster presentation (via http://friendfeed.com/steveko...)
0818091233.jpg
Steve Koch
ScreenToaster - How to create a keyword based RSS feed from PubMed From Colby on friendfeed: - http://www.screentoaster.com/watch...
ScreenToaster - How to create a keyword based RSS feed from PubMed From Colby on friendfeed:
Steve Koch
#scio10 You are all invited to ScienceOnline2010! : A Blog Around The Clock - http://scienceblogs.com/clock...
Kochlab
Steve Koch
http://www.youtube.com/watch... If you're interested in spinning things in the lab, or just clever engineering, take a look at Andy's latest invention. An inexpensive method for spin coating coverglasses with lipids. Was really impressive to see him conceive and build the device.
http://www.youtube.com/watch?v=C3oXdlWQg5I If you're interested in spinning things in the lab, or just clever engineering, take a look at Andy's latest invention.  An inexpensive method for spin coating coverglasses with lipids.  Was really impressive to see him conceive and build the device.
Play
See also his open notebook page: http://openwetware.org/wiki... - Steve Koch
Kochlab
Lab Recap: Anthony's Work - http://kochlab.blogspot.com/2009...
Steve Koch
Borisy Lab: Electron Microscopy of the Cytoskeleton of Cultured Cells (reprint 1998 paper) - http://www.borisylab.northwestern.edu/pages... (via http://friendfeed.com/steveko...)
Steve Koch
I think I am close to having our most important feedback module working w/ upgrades to DAQmx in LabVIEW 7.1 and on XP machine. It's at least to the point of compiling and I think the data structures make sense.
Piezo ramp compiling with new DAQmx piezo.png
Steve Koch
Kochlab
Steve Koch
10 Stupid Lab Safety Mistakes (Bitesize Bio) - http://bitesizebio.com/2009... (via http://friendfeed.com/the-lif...)
Steve Koch
Drew Endy's first blog post: State of the OWW | OpenWetWare Community - http://blog.openwetware.org/communi...
An excellent "state of the OWW" and call to action for all OWW users and potential users. - Steve Koch from Bookmarklet
An important discussion - where does it all go? And at the end of the day are we prepared to pay for it? - Cameron Neylon
Thinking... - Heather
Steve Koch
Video showing Larry's microtubule tracking software. - http://www.youtube.com/watch...
Video showing Larry's microtubule tracking software.
Play
The top right image is the original grayscale movie. The top left shows one individual MT tracked and thresholded (binary). The bottom left is entire image thresholded. The software is really slick! Written in LabVIEW, using NI Vision. - Steve Koch from Bookmarklet
Andy Maloney
KochLab now has it's very own optical tweezers!
Steve Koch
Cameron's OA Papers: Head In The Clouds - Automated Experimentation - http://cameronneylon.wikidot.com/head-in...
If you have time, start reading this! Now is the time we can really adopt some innovations in terms of our automation of data capturing and lab notebooks. - Steve Koch from Bookmarklet
Steve Koch
The Randomly Grad Life: The real name of my girlfriend - http://gradness.blogspot.com/2008...
Important info on Stef's name - Steve Koch from Bookmarklet
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