The title is a bit generic, isn't this what Phil Bourne's been doing? - Ruchira S. Datta

I think this is an extension of their (Kieser et al) previous work with SEA - Rajarshi Guha

Nature has a story on this in their news section: http://www.nature.com/news... - Michael Kuhn

Is this using Lasso or similar program? Interesting appearance of DMT as a molecule of interest - I have a student doing a report on it this term http://getcheminfo.wikispaces.com/Adam+My... - Jean-Claude Bradley

Uses SEA http://sea.bkslab.org/ - Rajarshi Guha

Thanks Rajarshi - looks like another cool online resource to explore - Jean-Claude Bradley

That's cool. How likely is the top match to be a real inhibitor? - Andrew Lang

We're trying to run our virtual library of Ugi products we can make in my lab http://usefulchem.wikispaces.com/UClib00... I hope that isn't too large a task - Jean-Claude Bradley

We did some of this validated cross-target prediction also http://www.nature.com/doifind... - Matthew Todd

That's awesome Mat! What would be the next step to processing our Ugi product library on the TDI kernel? - Jean-Claude Bradley