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Jeremy Leipzig › Likes

Pierre Lindenbaum
Bora Zivkovic
If you are in bioinformatics (or anything really), and are not associated with a University, what services and databases you'd like to have and use, but they cost money (so you don't, or you pay while cussing and cursing because it's impossible to work without)?
Although slightly rephrasing the question, I would like to be able to pay money to have a version NCBI that didn't make me want to gouge my eyes out with a spoon. - Paul J. Davis
I work at a small biotech company and as Neil said, access to journals is the biggest issue. We are associated with a university so when I'm there I can access journals, however normally from the company building I can't. The delay is frustrating. In terms of commercial tools/databases, currently I would like access to Genelogic gene expression database and Biobase transcription factor database and analysis tools. - Greg Tyrelle
Another small biotech here, and yes, access to journals is a huge pain. - Bill Hooker
I'm currently at a university, but was considering being an independent scholar for year or two (= a homeschooling mom with a research rather than a knitting hobby). Resource problems I anticipated: access to journals, Scopus subscription, Web of Science subscription. - Heather Piwowar
Thank you all - just as I expected: access to journals (and ways to find journals/papers) is the most expensive and most difficult to get thing if one is outside of University. How about space for office (lab?), equipment (poster printer?), software - if you were a researcher at home (freelance scientist) what would you need that costs? - Bora Zivkovic
Depends what kind of research. I'd need a biosafety hood, liquid nitrogen storage, glassware, balances, electrophoresis equipment, culture incubators, autoclave, chemical store... :-) - Bill Hooker
Software is the other bit. Biotech's tend to be a lot more budget constrained than many academic labs. - Deepak Singh
Access to journals and availability of equipment are both big deals, but whereas some equipment can be obtained from ebay or a local lab equipment company, academic literature database subscriptions can't be obtained at a discount rate. (AFAIK) - Mr. Gunn
For journal access, try getting yourself an unpaid appointment as affiliate faculty (aka courtesy appointment) at your local university. I've known a couple of people who have done that. - Donnie Berkholz
Lab space outside of a university or big company is very difficult to find. The so called "incubators" are expensive. It is still unclear to me what the rules are for running labs in commercially-zoned properties. - Jeremy Leipzig
Access to journals is a huge issue. My biggest expense for freelance science (computational biology) is the computing equipment; second would be software. - Walter Jessen
As I'm considering becoming an independent scientist (again!), some time ago I did back-of-the-napkin calculations and it turned out that I might need ca. $100 (reliable internet connection) + $500-1000 (per article payments, no subscriptions) + $500-1000 (computing cloud, storage and calculations) a month to work comfortably outside of academic infrastructure (without spamming all my... more... - Pawel Szczesny
Access to journals is the biggest issue. Obtaining this access by being an adjunct faculty is much more valuable than the salary they pay for your services. Obtaining funds to attend scientific meetings and to cover publication costs isn't far behind. Not always trivial to convince business types there is value in publishing your basic research. - Jeff Habig
Donnie, good to know re: affiliate positions, thank you. - Heather Piwowar
I'd be in Pawel's boat. On the software end, I can probably make do with open source. - Deepak Singh
Attila Csordas
checking the long post quickly RT @genomicslawyer What Five FDA Letters Mean for the Future of DTC Genetic Testing: http://www.genomicslawreport.com/index...
good discussion there - Jeremy Leipzig
Jan Aerts
I'll be giving a talk on "MongoDB and academia" at a #mongodb conference in London
Benjamin Tseng
Will this get hospital personnel to wash their hands? PNAS: Its possible to track bacteria to the hands they came from - http://www.pnas.org/content...
"Recent work has demonstrated that the diversity of skin-associated bacterial communities is far higher than previously recognized, with a high degree of interindividual variability in the composition of bacterial communities. Given that skin bacterial communities are personalized, we hypothesized that we could use the residual skin bacteria left on objects for forensic identification, matching the bacteria on the object to the skin-associated bacteria of the individual who touched the object. Here we describe a series of studies de-monstrating the validity of this approach. We show that skin-associated bacteria can be readily recovered from surfaces (including single computer keys and computer mice) and that the structure of these communities can be used to differentiate objects handled by different individuals, even if those objects have been left untouched for up to 2 weeks at room temperature. Furthermore, we demonstrate that we can use a high-throughput pyrosequencing-based... more... - Benjamin Tseng from Bookmarklet
you have to wonder if there is some business opportunity here. I saw George Poste give a talk in which he said there was some interest in using feces forensics for national security - basically the gut flora giving away that you were in an Al-Qaeda training camp for a month instead of Disneyland. - Jeremy Leipzig
I wouldn't be surprised if there were; if US insurance companies ever got off their butts and started actually managing risk/cost rather than just denying coverage, I can see them using technology like this to lower complications from hospital stays - Benjamin Tseng
Pierre Lindenbaum
Dont write code you wouldnt want to inherit.
Abhishek Tiwari
Do scientists really need a PhD? : Article : Nature - http://www.nature.com/nature...
"Young scientists at a Chinese genomics institute are foregoing conventional postgraduate training for the chance to be part of major scientific initiatives. Is this the way of the future?" - Abhishek Tiwari from Bookmarklet
and you can order that latte with amazing accuracy. - Mickey Schafer
Please delete this post - it could be infectious. All it takes is for a few undergraduates to get wind of this and you could tip over the whole apple cart. - Jeremy Leipzig
Too late, don't tell my PI (Steve Koch) but I'm leaving the lab now. I knew I didn't have to work for free for a chance to be successful! - Anthony Salvagno
with or without a frothy introduction... - Mickey Schafer
Why do mathematicians need PhDs? Discussion from diybio.org: http://groups.google.com/group... - Mackenzie Cowell
@Mark, another idea before its time: http://testingtfv.blogspot.com/2007... - Steve Koch
@Anthony you said you were going to the library to make photocopies??? - Steve Koch
Attila Csordas
just got an offer of employment from EBI for the position of Bioinformatician, details later, happy
woooo ! congratsAttila ! - Pierre Lindenbaum
Thanks, Pierre. Been working hard to make the jump between experimental biology & bioinformatics - Attila Csordas from iPhone
Congrats! Sounds like a great opportunity. - Heather Piwowar
congrats! - imabonehead
Congrats! Great news: welcome to the Silicon Fen. - Matt Wood
congrats, Attila! What will you be working on? - Mr. Gunn
Congrats Attila !! - Khader Shameer
Thanks, appreciate the support, it's definitely a proteomics job, exciting horizon - Attila Csordas from iPhone
Congratulations! Where will you be based? - Berci Mesko, MD
Congratulations!! - Yann Abraham
congrats :) - Pedro Beltrao
Congratulations! - Ruchira S. Datta
Woot - glad to see that the mass take over of EBI continues apace... - Cameron Neylon
How so take over? Is there anything you do not like about the EBI that requires take over? - Egon Willighagen
No, no. Just that we seem to be gradually getting people we know into positions there. Duncan, Nico, now Attila...not so much a takeover as an _enhancement_ - Cameron Neylon from twhirl
Congrats - Abhishek Tiwari
Thank you all! (Berci: EBI is @ the Genome Campus in Hinxton, we'll be based in Cambridge) Looking forward to meet all the Cambridge/Sanger/EBI people there - Attila Csordas
Congratulations! - Kubke
Congrats Attila :) - John Cumbers
Great! Congratulations! - Konrad Förstner
And of course my congratulations too, Attila.....looking forward to meeting you in person (finally)... - Nico Adams
thanks again to everyone, accepted the offer today with an April start date. - Attila Csordas
Congrats Attila! Read this on my handheld and thought you said the "FBI" instead. Does this mean the next BioBarCamp will be in the UK? - Jim Hardy
Nice, congrats! - Sung W. Lim
HI/congrats!--I think my friend John Tate works there...if so tell him I said hi! - Mary Canady
Jim: thx, there's BarCamb in Cambridge http://barcamb.org/ & BarCamb3 is happening on the weekend of the 24th – 25th April so I'm not sure about BBC. Sung, Mary: thanks, will find John Tate. - Attila Csordas
Deepak Singh
Hadoop World video is out - http://mndoci.com/2009...
Only took, what, 2 months to post this... - Shiran Pasternak
Watching now. BTW, you've convinced me to try "hundreds of slides" approach some day - I wasn't sure it works in more scientific talks. - Pawel Szczesny
Pawel, I wasn't sure either, but I've had a chance to do deeper dives now (at Supercomputing) and it seems to work, especially as I get more comfortable talking science in this format. If I had to choose an alternate one it would be a pure storytelling/figure format, i.e. about some of your core results and work backwards if required. - Deepak Singh
that was a really great talk! - Jeremy Leipzig
Jeremy, thanks - Deepak Singh
Pierre Lindenbaum
ISS020-E-09048_lrg.jpg (JPEG Image, 1440x960 pixels) - http://earthobservatory.nasa.gov/images...
ISS020-E-09048_lrg.jpg (JPEG Image, 1440x960 pixels)
fortuitous orbit of the International Space Station allowed the astronauts this striking view of Sarychev Volcano (Kuril Islands, northeast of Japan) in an early stage of eruption on June 12, 2009. Sarychev Peak is one of the most active volcanoes in the Kuril Island chain, and it is located on the northwestern end of Matua Island. - Pierre Lindenbaum
Pierre Lindenbaum
A few nightmares before biohackathon 2009. - http://plindenbaum.blogspot.com/2009...
Same nightmare about getting out of the airport. They do _not_ speak English, so how do I get from Narita to the hotel???? Day of Googling ahead. - Jan Aerts
fortunately a relative will be at the Airport and will wait for me. Jan, FYI I'll land in Tokyo tomorrow 14th at 14H00. - Pierre Lindenbaum
Ha! Is the "I know what I've seen" one a reference to "Watchmen" or "Twilight Zone"? - Chris Lasher
Take the Bus. There is a bus service that takes from from Narita into Tokyo hotels (by zone). Narita is a ways away from tokyo, so DO NOT TAKE A CAB. - Deepak Singh
@Chris What ? You don't know Grendizer http://en.wikipedia.org/wiki... ? Where were you in the late 70th ? :-) - Pierre Lindenbaum
Deepak Singh
Using R and Ruby - slides from February LRUG - http://blog.chrislowis.co.uk/2009...
R and Ruby - belongs in a Ruby for Bioinformatics room - Deepak Singh from Bookmarklet
That's an interesting blog. Using Jekyll too. - Michael Barton
Pierre Lindenbaum
Taxonomy and Semantic Web: writing an extension for ARQ/SPARQL - http://plindenbaum.blogspot.com/2008...
Pierre Lindenbaum
@Chris Lasher : "89 databases: 51 reported that they are struggling financially. Seven of these have closed; the rest are being updated sporadically in their owners' spare time." - http://www.nature.com/nature...
jeter.jpg
One of the DBs cited in the article, BIND, was operating next door to the lab I was working in 2005. They closed shop and the data was sold to Thomson Scientific. - pn
I remember when BIND went commercial ..all sorts of web-services suddenly broke(changed URLS )and were partly inaccessible. Its sad that we have free web-email but no money for persistent hosting of these resources. Maybe we should assemble a bioinformaticians-sans-frontier to rescue these services and port them to the cloud ( google-app-engine , amazon and other such services) - Hari
@Hari Wouldn't it be nice? - Chris Lasher
How'd you pay for cloud resources? - Rajarshi Guha
It'd be good to repeat this kind of survey now (that data is from 2005). Maybe a good Biogang project? Get all the databases from six months of Bioinformatics (or pick a NAR databases issue) from, say, three years ago and see how they're doing? - Euan
@Euan Wasn't it done last year ? I don't remember who's done the job. - Pierre Lindenbaum
we started just to check if they were online and if they worked but we never finished. - Pedro Beltrao
NIH has an active PA for "Continued Development and Maintenance of Software" (http://grants.nih.gov/grants...) which even dates back to 2002. Wonder how many grants have been funded off of it... - Andrew Su
Great data point... Agreed with Euan that this kind of survey needs to be repeated. Ideally, one would re-contact the databases contacted in 2005 in order to update the data, and then also contact databases mentioned in a new collection of issues. - Hilary
One could create a shared spreadsheet on google-doc, with each database and its current status. - Pierre Lindenbaum
It's almost worse if a one-off database stays up abandoned with old data. I bear some major guilt here - the Alternative Splicing Gallery (my thesis project) is still running with ESTs from 2003 and consistently gets 130 unique visitors a month. There is no simply no mechanism (guilt doesn't count) to maintain a program that is created for the purpose of getting a paper published. - Jeremy Leipzig
@Pierre @Hilary Something like Michael Barton's survey? http://tinyurl.com/6gs6pq - Chris Lasher
I guess more like http://bioinformatics.oxfordjournals.org/cgi..., 404 not found: the stability and persistence of URLs published in MEDLINE - pn
Chris Lasher
Duncan Hull | Semantic Matching of Bioinformatic Web Services - http://www.cs.man.ac.uk/~hulld...
Duncan Hull's thesis. - Chris Lasher
Duncan, is your thesis available somewhere as a pdf document ? I've the feeling it contains many things I'd like to learn about taverna, biomoby etc.... - Pierre Lindenbaum
Likewise, but at the bottom of the page it says Duncan says he'll publish it soon, he just has to make final corrections. - Chris Lasher
I'm also very interested in giving this a read. Please let us know when it's available :-) - Ricardo Vidal
@Duncan , that would be great: plindenbaum yahoo fr - Pierre Lindenbaum
@Duncan chris DOT lasher <AT> gmail TOD com - Chris Lasher
wouldn't it be great if we created an email list? - pn
Excellent idea, Paulo. Any ideas (interested) FF'ers as to how best to take this forward? - Graham Steel
It is possible to create a simple mailing list and have full access by everyone of everyone's info. - pn
I've set up a Mailman server before. I don't know if that does what you want. It sounds more like you're looking for an email registry. FWIW most of us have our email listed somewhere on one of the services published through FriendFeed. - Chris Lasher
yes, we do, but if we need access to someone else's email we don't have it at hand. I have a mailing list in my ISP's server, but that's not handy. - pn
Google groups? - Rajarshi Guha
Nice one, Rajarshi, didn't know about Google groups http://groups.google.com/ - Graham Steel
Rajarshi may be on to something. Groups provides mailing list support, as well as support for wiki-like pages. We could choose to publish our emails on that. Still, my Spidey Sense says we're re-inventing the wheel. - Chris Lasher
Most of us are connected threw LinkedIn. The e-mail are available to the direct contacts. - Pierre Lindenbaum
maybe a Ning network would solve this problem - Jeremy Leipzig
Andrew Su
Yann Abraham
Ruby for Bioinformatics
Scott
A Clean Break: Modern Prefab Comes to Philadelphia - http://www.treehugger.com/files...
Bora Zivkovic
Yikes! Someone screwed up majorly....
ObamaMccainNature.jpg
It is funny. A silly mistake, but embarrassing nonetheless. - Bora Zivkovic
or someone with a daring sense of humor :-) - Björn Brembs
Neither silly nor embarrassing... just very, very funny. - Richard P Grant
I've heard politics described as a dog and pony show... - Richard Akerman
sighs - Graham Steel
@Bora Yikes I'm surprised it made the Times. Ouch. - Richard Akerman
Something to point to, next time the argument comes up about Nature (or any journal) accepting or refusing papers in order to please advertisers. Pretty clear that the editorial hand has no idea what the advertising hand is up to. :-) - Bill Hooker
Wow...definitely a sily mistake but...damn - Rah-PM 2012
This is just beautiful :) Are they ALL wearing red ties / collars? "...stirs up a strong desire to tickle John McCain behind the ears" haha. - Jo Brodie
Jan Aerts
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