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Following yesterdays #MB1030 lecture on haemoglobinopathy and to supplement my knowledge of the topic, i found this useful website for anyone who would like to know more about this area. http://www.oup.com/uk... I find it an particularly interesting area, especially concerning the genetic disease element of the...
Separable roles for Exonuclease I in meiotic DNA double-strand break repair. - http://www.ncbi.nlm.nih.gov/entrez...
After prof Fry's lecture on cell division and cancer, i was very intrested in the mechanism of cell growth and repair. I found this article relevant to prof Cundliffes lectures (#BS1015)too as it relates the role of some exonuleases to DNA break repair as where prof Cundliffes lectures were about their role in DNA translation and ribosomal assembly. - Logan Windell
The nature of the ferryl heme in compounds I and II. - http://www.ncbi.nlm.nih.gov/entrez...
This article makes an interesting accompaniment to the lecture in myoglobin/haemoglobin we had in #BS1015 yesterday. It goes into alot of detail but i find it an interesting and relevant topic to extend my interest and knowlegde in the subject. Find it amazing how much research and work has gone into finding out the nature of the intermediate compounds, the bonding and interactions of these. - Logan Windell
Researching the Genomics of Cancer medicine essay for #MB1030 and finding that there is so much information! Dont know what to write about or what wouldnt be relevant. At least the #CH1070 text went well, one less thing to worry about.
Looking forward to todays practical after finally finishing last weeks write up! Hopefully we are well on the way to completing our asseignment for #BS1010 as we have all the details planned =)
http://www.wellcome.ac.uk/News... #MB1030 Found this site for the essay we had set on friday; "What role is gemonics playing in cancer medicine".
Its gives a good description i believe of the title and may help people to write the essay. - Logan Windell
Found these sites really useful to fill in little bits of Prof Cundliffs lectures 7 and 8 that I didnt have time to get down. Also gave a nice flow of the whole process, really helping me understanding my notes. That seems to be the really difficult part! http://www.biologyreference.com/Ta-Va......
Found the #CH1070 lecture on Chemical equilibria a useful refresher after a long summer of no chemistry. Taking chemistry at A-level seems to have its uses for this course!
Can You Hear Me Now? The Truth about Cell Phones and Cancer http://www.scientificamerican.com/article...
I don’t know about anyone else, but I certainly breathed a sign of relief when I read this article. It has always been strange to me that they would cause cancer since it was known the levels of radiation they emit are weaker than many constantly occurring forms of radiation, yet a few years ago there was a huge scare about the link between mobile phones and cancer; Probably the media getting totally the wrong end of the stick as in many cases. Still a relief though, would worry me if my molecules were coming part while I was talking. - Logan Windell
This article demonstrates exactly my doubts about the claims for links between mobiles and cancer- surely the radiation they emit would be no more dangerous than using your microwave every day or doing something as trivial as listening to radio/watching tv. - Rachel Bell
A View to a Kill: New Imaging Watches How Mitochondria Change During Disease A new imaging technique shows how diseases work in real time http://www.scientificamerican.com/article...
I was busy doing the online source analysis for MB1030 when I happen to come across this article on mitochondria and how they can damage us biologically. I thought it was very interesting that they have found an imaging technique to show how diseases work in real time. This will certainly help us to understand more about diseases that have so far puzzled many; such as Alzheimer’s and Parkinson’s and will inevitably help to develop treatments against them. Amazing how one simple lecture exercise can make you want to know more about a subject. =] - Logan Windell
Thinking about it more, this may actually be a useful technique to use in a possible third year project..... - Logan Windell
How We Are Evolving New analyses suggest that recent human evolution has followed a different course than biologists would have expected http://www.scientificamerican.com/article...
This is a really good, short article scientific America which seems to have sparked off quite a debate thread on the site. The process of evolution by natural selection I find so captivating, and here we can see that in action for ourselves with the Tibetans and their adaption to their environment. What does make this article interesting in my opinion is the fact that here it combines this with technological adaption as well, not merely genetic, which makes for an interesting thought. - Logan Windell
Parkinsonian Power Failure: Neuron Degeneration May Be Caused by a Cellular Energy System Breakdown: http://www.scientificamerican.com/article...
It is so amazing to be reading about advances being made to the understanding of the genetic defects that cause Parkinson’s disease to develop, and that they have actually been able to find a viable way of treating early onset of the disease in patients. The idea of this “master switch” protein is intriguing, and that it is able to interfere with the natural cycle that would lead to the continued development of the disease makes it hopefully the first step to find a cure to stop the disease in its tracks. - Logan Windell
"The most exciting result is the discovery of PGC1-alpha as potential new target of therapy for early intervention" This is indeed a very good article and a very relatable piece, something the Biological sciences courses could easily lead to. It is interesting to learn about the importance of mitochondria in relation to Parkinson's, something I hadn't considered whenever I thought about it. - Thomas Webber
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