#BS1005 or #MB1005: I have forgotten why the sum of the intervals (between genes) does not exactly equal the map length and cannot find an explanation in the lecture notes (Dr Meacock's 6th Lec).
"Length of map is sum of lengths of intervals" It just doesn't equal 100%. Does this help?
- Thomas Webber
I think his question means why ro and ss is 28%? (see Dr Meacock's lecture 6th page 14) e and ss and e and ro is 12% and 20% respectively so if add them together, it should be 32%. Why 28%? I remembered Dr. Meacock explained this but I have forgotten too.
- Sha Tim Wai
i m not sure about this but i think that, length between genes using RF values are just representing the relative positions of the genes in relation to the other. Don't forget that cM values on a gene map can have any value (there is no theoretical maximum) whereas for RF values there is a maximum of 50%
- Christos Kyprianou
correction: cM values represent relative positions of the genes (not RF values). RF values represent the probability of crossing over between 2 positions
- Christos Kyprianou
Here is a nice, short article that arguably has links to all of the module studied this term. It particularly links #MB1004 and #MB1005. Certain diseases can be studied using a neurotoxin from spider venom that blocks receptors that are also blocked in the development these diseases. As it is not possible to extract the venom from the spiders in large enough quantities to work with, the toxin gene has been inserted into plasmids and the recombinant DNA transformed back into E. coli. The toxin is then produced and harvested in a similar way to which insulin would be harvested for diabetics.
- Max Levin
from Bookmarklet
I haven't posted in a while on friendfeed as I have been both busy and lazy. I am back though and, as I have already hinted, think there has been quite alot of work recently. Presentations, posters and report in most module have meant there has been more work than last semester. #BS1011 has also increased in difficulty. Whilst being quite good at maths, I've always struggled with statistics, perhaps through lack of interest, but now I can see its application to my degree stream I'm less apprehensive. I really enjoyed the #BS1006 practical two weeks ago and was intrigued to see the difference in breathing rates/volumes between rest and exercise. Hopefully the one tomorrow will be similar, off to go and read up on that.
- Max Levin
"Students often think of microorganisms in negative terms. Negative attitudes are supported by the public health and media focus on microbe-caused diseases as well as advertising for microbe-destroying soaps and cleaners. Although reducing disease transmission is important for individual and community health, students also need to understand the beneficial contributions microbes and microbial communities provide. Quite a few online resources focus on microorganisms and disease. For this review, I sought resources that educators can use to help students in introductory and nonmajors biology courses understand the beneficial contributions of microbes."
- Dr Alan Cann
from Bookmarklet
students interested in beneficial side of microbes should take #BS3068 "Microbial biotechnology" where the spin is mostly positive... except my lectures on antimicrobials ;o)
- Dr Chris Willmott
I might well take that module, love a bit of biotechnology, me.
- Max Levin
I am interested in the pathology on pathogenic bacteria. but I am studying biochemistry stream now. Do we have some modules on bacterial or virus pathology in biochemistry?
- Sha Tim Wai
You will have opportunities to take microbiology modules in the 2nd and 3rd year.
- Dr Alan Cann
Laboratory practical notebook: 15% Practical books are to be handed in to Room 129/130 MSB by 12.00 noon Thursday, 3rd March 2011. Please label them for the attention of your demonstrator (this means you will have to know his/her name!!). (BB-->BS1009-->assessment)
- Max Levin
Here is good article that discusses a question I have often asked, relating to #BS1009. Viruses are interesting to me because they so far seem to be the group of 'organisms' closest to being 'dead': note how Stanley won the Nobel prize in chemistry, not in phsiology! Seeing in the #BS1009 lectures how simple viruses can be poses the even more complicated questions 'What is life?' and 'Will we ever know?'
- Max Levin
from Bookmarklet
I think the statement, 'viruses lead a borrowed life,' is how I look at it. Essentially 'Dead' in the inactive form but as good as alive within host cells. I don't think we will ever know what life is because it is such a complex question to answer simply but it is an interesting topic/debate.
- Arnold Gangaidzo
That's not a bad outlook. Personally I think life is an illusion, like time. I think we are as alive as viruses and they are as alive as rocks. Controversial, I know.
- Max Levin
I recently recieved my results for the first semester exams and am currently working at a high 2:1. This is what I expected although I'd like a first class mark at the end of the year (and degree) so need to get my head down to bring up the average. I just completed this weeks #BS1011 assessment and got 100% so pleased with that (heading tin the right direction hopefully). Earlier I enjoyed the #MB1031 lecture on how to improve our report as I found I'm doin all the calculations correctly, though I need to improve my written content later today. Off now to the #BS1009 lecture on BIOTECHNOLOGY. Can't wait as I'm already interested in this area but it should, moreover, help with writing the module essay on microbe use.
- Max Levin
Yay, my #MB1031 scientific report on isozymes is complete. Hopefully it's a good one, I can't wait for our lecture tomorrow for more information on it to help me adapt it and make it better!!
Max, that sentance makes no sense whatsoever.....
- Philip Higgs
Checking it through for you now, and it seems pretty good to me! :)
- Grace Allison
Oh dear aha. basically. what is your word count?
- Max Levin
Thank you Grace, I will try to eloquentise my title for you though. Max, my word count is 633. And I have good Line-weaver Burk plots and tables =)
- Philip Higgs
haha, it was only a friendly suggestion. and, yes, your Lineweaver-Burk plots are very clear, I will agree with you there.
- Grace Allison
The #BS1011 work this week was a little more challenging but luckily excel isn't actually the worst thing ever as with a little exploration and intuitive thinking most things become self explanatory. Last week’s #MB1005 practical was a step up too and I struggled with some of the concepts dealt with so need to read over the lecture notes to give myself a clearer understanding. I’m a little bit apprehensive about writing the report for #MB1031 as I’m quite slow at written pieces. At least I know what I’ll be doing this weekend.
- Max Levin
"A renowned University of Leicester ecologist who has spent over 30 years researching wetland conservation at Lake Naivasha in Kenya has warned that the country is being “bled dry” by the UK’s demand for fresh flowers. He called on UK supermarkets to show more concern about the health of the natural environment that the flowers come from. Dr David Harper, of the Department of Biology, University of Leicester, said UK supermarkets should do more than simply selling “Fair Trade” roses. They should look beyond the farm gate at the sustainability of the natural resource that feeds the flowers - Lake Naivasha."
- Dr Alan Cann
from Bookmarklet
More western ignorance, I see. It's ironic how in trying to please one person for a moment, we completely forget about a whole nation and its future.
- Max Levin
Ok. I guess I should just ask for Diamonds- hmmm...Im sure that doesnt have any ethical issues??
- Remi Mckenzie
Good first week and good start to this week. I've done all my short-term compulsory work, I just need to start the #BS1009 module essay as I have only briefly researched it so far. I also need to make notes on lectures by combining my lecture notes and the blackboard notes, a technique that served me well last semester. Off now to read over tomorrow's #BS1009 practical.
- Max Levin
I have answered all the questions for the first #BS1011Excel assessment and all my formulae work but I'm afraid to submit the answers incase they're not in the most simple form. I can't see how I can simplify any of them but also I haven't used excell in along time and, for the most part, I've never used the formula before. Should I just submit?
Pages like this provide a useful base of information (esp. paragraph 6 and below) that can be expanded upon later. I will research the topics mentioned in more detail, particularly the use of biotechnology in vaccines for use in the #BS1009 module essay entitled 'How would you convince a friend that microorganisms are more than just disease causing agents?'.
- Max Levin
from Bookmarklet
As far as I understand, oil has a higher resolving power than air so is used in accordance with high magnification objectives to maintain clarity.
- Max Levin
it is used to enhance the resolution i think
- Mehrine Elahee
Over the past month I've been working pretty hard so it was good to have a break at the end of last week, although mine was late starting as I had to give my #MB1030 presentation to Dr Willmott on thursday morning when everyone else was probably in bed. Looking forward to the new semester and I have better attitude already, so I should be more focused. I thought the #BS1009 lecture today gave a good overview microbiology and, as I'm already interested in biotechnology, I'm sure I'll enjoy the module!
- Max Levin
Hippies do an interpretive dance of protein synthesis. I just wish I'd found this a couple of weeks ago. Still brilliant though (it gets wild about 3 minutes in). http://www.youtube.com/watch...!
BBC iPlayer - Horizon: What is One Degree? Ben Miller investigates scientific accuracy. He meets researchers working with extremes of temperature and experiences some of the strangest effects of quantum physics. - http://www.bbc.co.uk/iplayer...
topoisomerase II is also known as DNA Gyrase whereas i believe this differs from topoisomerase I which has a different function.
- Arnold Gangaidzo
Topoisomerase I catalyses the relaxing of super coiled DNA whereas DNA gyrase (topoisomerase II) utilises free energy from ATP hydrolysis to add negative supercoils to DNA. Type I does this by cleaving one strand of DNA whereas type II will cleave both strands. Read Stryers pg. 790. Thanks for the post...got me recapping!
- Arnold Gangaidzo
Gyrase is a bacterial example of a type II topoisomerase (topos). Type II topos cut both strands of the DNA whereas type I cut only one. There are other type II topos, for example another bacterial one called Topo IV. There are eukaryotic type II topos too (sufficiently different not to be affected by the same antibiotics). So gyrase is an example of a type II topoisomerase #BS1015
- Dr Chris Willmott
As far as I can fathom, because we wont have a new timetable till the 31st (the new semester) and we've finished all of our lectures for the modules we are being examined on, the time between exams will be mainly used for revision, though I'm not sure if our lecture slots will be filled with other activities. :)
- Max Levin
Lectures start on January 31st. The timetable is on Blackboard.
- Helena Hanschell
yo chris, fancy helping me with my last #BS1010 question? (please) :p its about mean doublings/hour
- Max Levin
@Max - this is an assessment. If there is evidence of you colluding with other students you could be accused of plagiarism. Inappropriate comment.
- Dr Alan Cann
the pass rate was 40%, the exam was marked out of 200 - so last IT and numeracy question for this term - how many marks did you need to score to pass?!!
- Dr Jo Badge
@max percentages are fractions of 100. the test was marked out of 200. So 40% is 40 marks out of 100, so therefore 40% of 200 is 2 x 40 = 80 marks. Did you score more than 80 marks? then you passed :-)
- Dr Jo Badge
I am not sure if there was pass and fail?
- Aisha Shakel
I passed it. Pleased with the marks I got compared to the effort I had put in1.
- Paskuwal Kosalie Mendis
I don't use any of those passwords, im suprised so many people do. Though for some sites they make you use a mixture of letters and numbers which should reduce the use of some of those.
- Rebecca Suter
Same, I don't use any of them but that's quite funny! especially how many people just put password!!
- Rachel Nolloth
lifehack, monkey and consumer were add passowrds to be so common. my password is a fortress lol.
- Max Levin
I dont use any of these password but I do have a bad habit of recycling the same password and altering it slightly :S
- Benjamin Tanner
Same as Ben. I think a lot of people do this though.
- Max Levin
Gotta admit I used the abc123 one for a website once, but I think it's because I had to sign up for a one off use. I use other methods now which allow for a unique password for every website that's easy to remember.
- George Woolnough
from iPhone
I never use any of these - I use ones no-one but me would know, and only a few very close friends/family even come close to guessing! I have the same bad habit as Ben and Max of reusing the same passwords (I have about 3 or 4 I use), but I like to think they're secure enough that no-one guesses them. Never been hacked anyway, so I think so!
- Susan Petherbridge
I never used any of the listed, but I also have to admit that I re-use the same password. Though to make it a little more secure, I use the same password but each time I change it slightly by adding a number.
- Katharina J Kusztelan
I have never used any of the passwords listed but it did make me laugh to see that monkey was a popular password and that people also used qwerty as well!! I have to admit I also use the same 3 passwords for everything, i find it is the only way I can remember them all without putting them down on paper. :S
- Grace Hodson
Translates literally into modern English as 'lots of excited'. A more appropriate translation would probably be 'very happy'. He got 21. Well done Max :)
- Christopher Lysons
thanks Christopher! And congrats 2 u Max, that is something to be v happy about!
- Maryam
Thanks guys, esp. Chris for translating! :)
- Max Levin