pathogen-associated molecular patterns and pro-inflammatory immunity - Fouad Boumezbeur

importance of bacteria of the gut which can act in symbiosis with host cells - Fouad Boumezbeur

symbiotic bacteria act on the immune system to maintain homeostasis - Fouad Boumezbeur

G. Eberl presents his team's work on IL-17 mediated pro-inflammatory immunity - Fouad Boumezbeur

Gérard Eberl, Institut Pasteur : gut residing segmented filamentous bacteria drive autoimmune T helper cells response - Fouad Boumezbeur

SFBs = segmented filamentous bacteria - Fouad Boumezbeur

modulation of immunopathology by Th17 cells - Fouad Boumezbeur

Segmented Filamentous Bacteria can cross the mucus to bind to the epithelial cells as pathogen and induce an important TH17 response - Fouad Boumezbeur

IL-22 production by RORgt+ ILCs is repressed by IL-25 - Fouad Boumezbeur

ILCs = innate lymphoid cells - Fouad Boumezbeur

[Ivanov et al., Cell 2006] : "the orphan nuclear receptor RORgt is a transcription factor of genes encoding IL-17 and the related cytokine IL-17F in naïve CD4+ T helper cells" - Fouad Boumezbeur