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F1000 evaluation of my recent paper - http://f1000.com/12177956
Some more shameless self-promotion here on FF - I wonder if there's anyone left here to actually read it... - Mickey Kosloff from Bookmarklet
I guess the lack of comments answered my question :-( - Mickey Kosloff
Not necessarily: http://en.wikipedia.org/wiki...; also it costs money to read that link. - Bill Hooker
I did not know F1000 evaluations were free to read... - Egon Willighagen
Deciphering the protein-protein specificity code | Human Frontier Science Program - http://www.hfsp.org/frontie...
HFSP summary of my Nature Structural and Molecular Biology paper. - Mickey Kosloff from Bookmarklet
My paper is *finally* online in Nature Structural & Molecular Biology: "Integrating energy calculations with functional assays to decipher the specificity of G protein–RGS protein interactions" - http://www.nature.com/nsmb...
My paper is *finally* online in Nature Structural & Molecular Biology: "Integrating energy calculations with functional assays to decipher the specificity of G protein–RGS protein interactions"
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De-Novo Computational Design of a Protein-Protein Interaction | Macromolecular Modeling Blog - http://rosettadesigngroup.com/blog...
Oh, that's sensational - Matthew Todd
Snake Oil? The scientific evidence for health supplements (updated and revised). - http://www.informationisbeautiful.net/play...
PHD Comics: The Grant Cycle - http://www.phdcomics.com/comics...
PHD Comics: The Grant Cycle
I have trained dozens of postdocs. - http://vadlo.com/cartoon...
I have trained dozens of postdocs.
In Person: Falling Off the Ladder: How Not to Succeed in Academia - Science Careers - http://sciencecareers.sciencemag.org/career_...
Wow! Painfully honest. Must-read for every PhD candidate! Never read anything like this... - Björn Brembs
My oh my. What a fascinating read. And not at all encouraging for one in very early stages of building some sort of a post-PhD career. - Gudmundur Thorisson
"This just does not happen in the male-oriented world of science in which, traditionally, dogs are keen to dine on dogs rather than share the bone between them, so to speak." ... not all male are like that... perhaps at the upper end of science they are... - Egon Willighagen
"Every scientist needs someone in a position of power who has faith in his or her abilities, to provide advice and do a bit of trumpet-blowing on his or her behalf." ... that's what I can relate to most... those do not have to be your supervisor, but you need one anyway, because there is no form to ask for some boon, it's just grabbing what is left over... someone passing some left overs is what keeps you going. - Egon Willighagen
I guess this is also why asking for some left-overs with others is rewarding... yeah, don't be afraid to ask that co-authorship... (never done that myself, but it is more common, though not openly, and I very much regret I rejected a direct co-author invite a few years ago) - Egon Willighagen
I don't understand - how one can be smart enough to become scientists and still believe to be "hard-wired"? Being successful in any area requires work on one's personality as well (for example becoming comfortable with talking to people) - and it's not "a rocket science". Sorry for harsh words, but this made me angry - I thought scientists are smarter than FoxNews audience. - Pawel Szczesny
@Pawel... it's where the balance is... right now you can get pretty far by sucking up and being with the right people, rather than being smart yourself, while at the same time these smart people fail because they are not good at that... is that what we want? I certainly don't... but it is indeed the current game play... - Egon Willighagen
Egon, I absolutely agree - current system is wrong on many levels. But we know the rules and we decide to play along or not (and that choice is a completely different story from what was written in this piece). Blaming failure on "hard-wiring" is like saying you're not "hardwired" to be good at World of Warcraft, because you tried it once without reading the manual and you didn't scored high. - Pawel Szczesny
I think that there is more than one way to succeed in science these days, and that there is no "one true path". However, and this is where this blog post comes in, there are also more than one way to fail, and in some cases you might not have full control over your path. - Mickey Kosloff
It is unfortunate that in many disciplines it's much harder to succeed nowadays based on science alone. Some excellent scientists are drawn to science *because* of their less-than-outstanding people skills and much later in their career find themselves disadvantaged by this. - Mickey Kosloff
I have to agree with Pawel. While unfortunate, the author had a pretty good run - tenured position etc. While women certainly have it harder in the sciences, complaining that you didn't do the networking because you didn't have the confidence is not a valid excuse. And to a large extent, networking is pretty core to any position of authority (and I consider tenure track profs to be in positions of authority) - Rajarshi Guha
The thing is, she makes out that she failed somehow. But she didn't. The system failed. There should be a place for people who want a normal life. - Noel O'Boyle
Pawel, Rajarshi -- I don't exactly disagree, but I think you are overlooking something crucial. You are clearly aware of the central role of networking, and perhaps you have always known that -- but for many of us (geeky types), it's an alien concept. It took me 20 years to figure it out, to the feeble extent that I *have* figured it out, and nowhere in any of my formal education was... more... - Bill Hooker
Bill, I see your point. Personally, I never thought I'd be able to talk in front of a group of people and I was painfully shy when I came to the US to start grad school. (I was quaking at my first GRC!) I suppose I was lucky that my advisor encouraged conference posters/talks. But from what I understood - the author of that article also attended conferences. But once you're at a... more... - Rajarshi Guha
I think successful social/networking skills also vary depending on your profession and type of job - successful skills in one profession don't always work well in other fields. There's also in-person versus other environments (email, phone, etc.) - Elizabeth Brown
Come to think of it, I've missed something too. It's not just that one is expected to absorb by osmosis the importance of interpersonal politics (and the skills to navigate those treacherous waters!). Equally bad, if not worse, is the Big Fat Lie Of Science -- that it's a meritocracy. We intuitively expect things to work that way, and from day one of grad school we're fed the Lie, that... more... - Bill Hooker
+1 for Bill's last comment. Science today is so competitive that, between getting your PhD and getting tenure (and often after), there's not a lot of room for mistakes along the way. Sometimes even if you make no mistakes bad luck is enough to derail you. I've seen enough good/potentially good scientists lose their way to realize it's not always about being smart and working hard (and networking well). - Mickey Kosloff
But what (that is worth doing) isn't competitive? - Rajarshi Guha
The point in science is that doing 'good' and 'exciting' science is (by and large) necessary but not (and this is exactly where Bill is right) sufficient for getting a job. In addition to the great results that others are interested in, there's a bunch of hard to control factors which, for most people, are best summarized as luck, circumstance or chance. As the saying goes, luck is a... more... - Björn Brembs
@Rajarshi: all those things that are co-operative instead. - Bill Hooker
Surely I agree about broken system which indeed requires quite a lot of other things than quality science. To come where we are everybody here needed to overcome some issues along the way (I have 20 years of experience of working on social skills/personality whatever you name it). That often wasn't necessarily a conscious effort but it doesn't matter. But I would expect that somebody with such experience as author (she was not a fresh PhD) would figure out that there's not such thing as "Nobel gene". - Pawel Szczesny
Yes, there's luck, fake meritocracy, broken system which doesn't suit women very much (although at my host institution at Polish Academy of Sciences ratio between women and men is 4:1), networking, area of competence, country of origin (I've tried to find PhD position before Poland joined EU - lots of fun, I tell you) and many other factors we can or cannot influence. But if somebody... more... - Pawel Szczesny
New Study Sheds Light on Spread of Swine Flu - NYTimes.com - http://www.nytimes.com/2011...
Should I Work for Free? Cool infographic. - http://www.shouldiworkforfree.com/
Wondering where reviewing papers fits in here... - Mickey Kosloff from Bookmarklet
How the case against the MMR vaccine was fixed -- bmj.com - http://www.bmj.com/content...
Happy New Year (with some light painting).
HappyNewYear2011-LightPainting.JPG
Doctoral degrees: The disposable academic | The Economist - http://www.economist.com/node...
Productivity shortfalls in drug discovery: Contributions from qualititative, consensus- dependent, technology-driven preclinical science? — JPET - http://jpet.aspetjournals.org/content...
"We have now found the gene for..." - YouTube - John Cleese - The Scientists - http://www.youtube.com/watch...
"We have now found the gene for..." - YouTube - John Cleese - The Scientists
Play
Yes, I know, it's from 2008. Some people (i.e. me) can be slow. Still seems quite relevant though ;-) - Mickey Kosloff from Bookmarklet
The Unsuccessful self-treatment of a case of "writer's block". - http://delong.typepad.com/sdj...
The Unsuccessful self-treatment of a case of "writer's block".
All work and no play makes Jack a dull boy... - Eric Jain
Phylo - Following FoldIt, now the game is about MSA. - http://phylo.cs.mcgill.ca/eng...
"What's Phylo all about? Though it may appear to be just a game, Phylo is actually a framework for harnessing the computing power of mankind to solve a common problem; Multiple Sequence Alignments." - Mickey Kosloff from Bookmarklet
Turns out my "postcard" from #ISMB2010 (3Dsig) was published more than 2 weeks ago: http://www.ploscompbiol.org/article... - about multiple conformational ensembles that can hide behind the seemingly static view of protein crystal structures (a talk given by James Fraser from Berkeley).
In Which We Learn That It Is Unwise to Drink and Handle Snakes | Wonderland | PLOS blogs - http://blogs.plos.org/wonderl...
In Which We Learn That It Is Unwise to Drink and Handle Snakes | Wonderland | PLOS blogs
Guess I should change my plans for tomorrow... - Mickey Kosloff from Bookmarklet
Scanning Dead Salmon in fMRI Machine Highlights Risk of Red Herrings | Wired.com - http://www.wired.com/wiredsc...
Scanning Dead Salmon in fMRI Machine Highlights Risk of Red Herrings | Wired.com
And now it's published: http://jsur.org/v1n1p1 - Mickey Kosloff
And Iddo blogged about it here: http://bytesizebio.net/index... - Mickey Kosloff
Scanning electron micrographs - Feeling chipper, the wood ant caught bringing science to life | Mail Online - http://www.dailymail.co.uk/science...
Scanning electron micrographs - Feeling chipper, the wood ant caught bringing science to life | Mail Online
Scanning electron micrographs - Feeling chipper, the wood ant caught bringing science to life | Mail Online
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Duke Joins Compact for Open Access to Scholarly Journals - http://news.duke.edu/2010...
"Beginning this month, any Duke faculty member, post-doctoral researcher, graduate or professional student whose article is accepted for publication in a peer-reviewed, open-access journal can apply to have associated article processing fees reimbursed." - Mickey Kosloff from Bookmarklet
Animals in the news - The Big Picture - Boston.com - http://www.boston.com/bigpict...
Animals in the news - The Big Picture - Boston.com
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Race and ethnicity mapped by block - http://flowingdata.com/2010...
Race and ethnicity mapped by block
Cool geo-visualization. - Mickey Kosloff from Bookmarklet
Why Parents Hate Parenting -- New York Magazine - http://nymag.com/news...
Climate change: Warming world | The Economist - http://www.economist.com/node...
Climate change: Warming world | The Economist
From a statistical point there, I see some interesting things... 1. the common pattern has clear trends during an era, and going up or down more than twice in a row is common (three times up triggers a signal in many process technological monitoring systems), 2. throughout the blue system, you see an overlap between consecutive decades of the normal distributions; that overlap does not... more... - Egon Willighagen
On my way to #ISMB2010 (July 8-13). Presenting a poster (W60) and will be talking in #3DSIG (Friday, 16.10, #51). Do come by (or email).
Ah, will be talking about "Structure-based redesign of protein-protein interaction specificity reveals mechanism and selectivity of G-protein turn-off by RGS proteins". - Mickey Kosloff
Locals and Tourists - Flickr city photos mapped - http://www.flickr.com/photos...
Locals and Tourists - Flickr city photos mapped
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