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Nicolas Palopoli
Biólogo computacional bajo selección natural. // Computational biologist under natural selection.
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A Slater on Comparison of structural alignments
#iscb_latam
March 20, 2012
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Very interesting talk by G Parisi. Worth looking further on conclusions about importance of conformational diversity.
#parisi
#iscb_latam
March 20, 2012
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'all the conformations are essential for protein function'
#parisi
#iscb_latam
March 20, 2012
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considering conformational diversity may assist in single-mutant diseases prediction
#parisi
#iscb_latam
March 20, 2012
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The natoive state is an ensemble of conformers
#parisi
#iscb_latam
March 20, 2012
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Keynote of Gustavo Parisi starting now: Conformational diversity and the development of new tools in bioinformatics
#iscb_latam
March 20, 2012
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excellent talk, brilliantly delivered by L Chemes. Congrats Lu!
#iscb_latam
March 20, 2012
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Linear motifs in E7 proteins do not cooccur randomly, with no clear coupling between evolution in ordered or disordered regions
#iscb_latam
March 20, 2012
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Lucía Chemes presents the evolution of linear motifs in the disordered and ordered regions of E7 viral oncoprotein. Go Lu Go!
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March 20, 2012
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L Bleicher looks for sub-classes determinants in protein families
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March 20, 2012
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Every single fold could be built combining known smotifs (wonder if what's more conserved is just local structure)
#iscb_latam
March 20, 2012
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PDB contains all possible smotifs (supersecondary structures, elements of secondary structures connected by loops)
#fiser
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March 20, 2012
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A. Fiser in Modeling proteins using a supersecondary library and NMR chemical shifts
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March 20, 2012
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similarity is the things in common, distance is the things not in common
#sippl
#iscb_latam
March 20, 2012
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RT @
nachoquique
:
#iscb_latam
#sippl
Finally someone explains to me the similarity (or distance) between the concepts of similarity and distance
March 20, 2012
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Arriba la unidad y el rol biológico! QT @
nachoquique
: @
NPalopoli
#iscb_latam
¡Abajo la estructura! ¡Estudiemos procesos!
March 20, 2012
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classify proteins, get to know everything about their structure, but biological role remains hidden
#sippl
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March 20, 2012
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two random sequences would share 6% identity, but 10-20% not enough to infer common ancestor
#sippl
#iscb_latam
March 20, 2012
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Day 2 starts with Manfred J. Sippl and Amazing Protein Folds. Good presentation from chair D Ferreiro.
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March 20, 2012
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J Ugalde presented High resolution community genomics of a hypersaline microbial ecosystem
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March 20, 2012
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G Riadi under the hypothesis of transposition during DNA replication, working with Composition Pattern Organization
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March 20, 2012
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AT Ribeiro de Vasconcelos presented the SABIA sequencing platform which includes all bioinformatics analysis needed
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March 20, 2012
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C Fresno gave us GOBoot and mentioned the SEA approach for ontology analysis
#iscb_latam
March 20, 2012
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SA Sansone present standards in bioscience compiled at
http://biosharing.org
and the ISA Commons
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March 20, 2012
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Before the second day starts, let's take a look at some of yesterday's talks in
#iscb_latam
March 20, 2012
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Run out of battery. Some comments on remaining talks to come this night.
#iscb_latam
March 19, 2012
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S-A Sansone presents The ISA Commons to help develop reproducible research
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March 19, 2012
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MSR-CA combines OLC and de Bruijn graphs for better assembly. Super-reads do not throw away information.
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March 19, 2012
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A Zimin on challenges in assembling NGS data
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March 19, 2012
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Life Technologies sponsored lunch. Talk includes presentation of two kits for synthetic biology and a gene synthesis service.
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March 19, 2012
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