Yep, open science works! My open dissertation outlines how to make a gliding motility assay using kinesin and microtubules. It took me nearly a year to perfect the procedure. It took a fellow graduate student at UCSC only two weeks to reproduce my procedures from my open dissertation and get the assay to work. Which, is not trivial and not easy.
I am making my dissertation writing completely open and based on my open notebook. Here's the first chapter. http://www.openwetware.org/wiki... This is in the rough draft stage but there is more to come.