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Re: The quarantine period for Ebola virus - http://www.virology.ws/2014...
"I linked to the article, read it and find out the methods." - Vincent Racaniello
Re: Firestone Did What Governments Have Not: Stopped Ebola In Its Tracks - http://www.npr.org/blogs...
"If this is all true, then I wonder why the health care personnel in Dallas could not avoid infecting themselves. It also shows that this type of protective wear is sufficient to stop spread. I am so tired of the cries 'Ebola has gone airborne' voiced after the Dallas infections. No, they just made mistakes." - Vincent Racaniello
Re: Would we have an Ebola virus vaccine if not for NIH cuts? - http://www.virology.ws/2014...
"I agree, and this sentiment was voiced by Tom Solomon in our discussion of this issue: http://youtu.be/XAPuwdlu0KI. Even if you have a vaccine, does not mean you will be able to use it effectively." - Vincent Racaniello
Re: Enterovirus D68 infections in North America - http://www.virology.ws/2014...
"EV-D68 has been circulating globally for many years. The data are in the Lipkin paper, linked in the article. The idea of an introduction into the US is not consistent with the data. Neither is postulating an increase in virulence: the genome sequences reveal that the virus in the US is garden-variety EV-D68." - Vincent Racaniello
Re: Would we have an Ebola virus vaccine if not for NIH cuts? - http://www.virology.ws/2014...
"I'm hoping we'll learn a lesson from this outbreak, and be ready for vaccines against a variety of deadly viruses that we don't think are important enough to warrant a vaccine. Because the moral is, you can never predict where a virus is going to spread. I suggest Marburg, Lassa, Sars, Mers, Nipah, Hendra. Probably others should be there as well." - Vincent Racaniello
Re: TWiV 306: This Week in Ebolavirus - http://www.twiv.tv/2014...
"We did discuss the definitions of 'airborne' on previous TWiVs, also on Transmission of Ebola virus. Droplet transmission is not defined as airborne, it is a form of contact." - Vincent Racaniello
Re: TWiV 306: This Week in Ebolavirus - http://www.twiv.tv/2014...
"Jahrling: "There seems to be a belief". Last time I heard, beliefs are not what drive science; it's data. It really bothers me when scientists speak like this, because the press does not know how to deal with it." - Vincent Racaniello
Re: Combination antiviral therapy for hepatitis C - http://www.virology.ws/2014...
"Yes, I did say the math applied to HIV-1. But you are correct on the Sofosbuvir cost, which would make it harder to get resistance to dual therapy than HIV-1. Do you know if triple therapy for HCV is being considered?" - Vincent Racaniello
Re: The incubation period of a viral infection - http://www.virology.ws/2014...
"At the beginning of this thread, CRS-DrPH wondered about the statement of no virus shedding during the Ebola virus incubation period. After having looked at the literature, one has to be careful, as it's based on epidemiological observations, not experimental ones. The fact that no one, apparently, has been observed to contract Ebolavirus infection unless they have been near someone with symptoms. But as someone says below, if levels of virus shedding are low, transmission might not be apparent epidemiologically. I'd much rather have laboratory data." - Vincent Racaniello
Re: The incubation period of a viral infection - http://www.virology.ws/2014...
"There are always going to be outliers, incubation periods that go outside what we write in a textbook. They are meant to be guidelines. Biology is never black and white." - Vincent Racaniello
Re: Virophage, the virus eater - http://www.virology.ws/2011...
"Even if you knew how virophages interfere with the replication of their helper virus, this mechanism would not necessarily apply to Ebola virus or HIV. But certainly it's worth studying how virophages interfere!" - Vincent Racaniello
Re: Treatment of Ebola virus infection with brincidofovir - http://www.virology.ws/2014...
"They are also going to use plasma of survivors to treat patients. The more different options, the better." - Vincent Racaniello
Re: The incubation period of a viral infection - http://www.virology.ws/2014...
"In biology nothing is ever black and white. I was surprised that Frieden said 'zero chance' instead of 'low probability' or some such word. However in animal models and in the limited number of humans studied, no virus is detected until symptoms arise. I will dig up the references at one point. When I make statements they are based on research, not speculation, unless otherwise indicated. However a blog is not a research paper, so not every statement is referenced." - Vincent Racaniello
Oral polio vaccine-associated paralysis in a child despite previous immunization with inactivated virus - http://www.virology.ws/2014...
The incubation period of a viral infection - http://www.virology.ws/2014...
Re: Acute flaccid paralysis of unknown etiology in California - http://www.virology.ws/2014...
"Or perhaps there were multiple causes. I'm sure CDC looked for commonalities and didn't find them. Or couldn't." - Vincent Racaniello
Re: Acute flaccid paralysis of unknown etiology in California - http://www.virology.ws/2014...
"Because the CDC did not detect poliovirus, or antibodies to poliovirus, in clinical specimens from the patients. AFP is used to identify patients who might have polio, but virus isolation or antibody detection is needed to confirm the diagnosis." - Vincent Racaniello
Acute flaccid paralysis of unknown etiology in California - http://www.virology.ws/2014...
Re: WHO on Ebola virus transmission - http://www.virology.ws/2014...
"There is no evidence that H5N1 transmits among humans by aerosol. These clusters of transmission that you list are not well understood and could represent droplet or contact transmission. For you to say that H5N1 can acquire 'efficient' human to human transmission is simply wrong. The point remains that no human virus has changed its mode of transmission, and you can pick any number of examples. Continuing to debate this point is not productive." - Vincent Racaniello
WHO on Ebola virus transmission - http://www.virology.ws/2014...
TWiV 305: Rhymes with shinola - http://www.virology.ws/2014...
Ebola virus enters the United States - http://www.virology.ws/2014...
Re: Could the Ebola virus epidemic have been prevented? - http://www.virology.ws/2014...
"We have many vaccine candidates, monoclonal antibody therapy and some antivirals. Many are ready for phase I. In this case half a billion might be enough. But you are right, the conventional wisdom is that bringing a drug to market costs about a billion dollars. This is nothing compared to what the outbreak is going to cost." - Vincent Racaniello
Re: Could the Ebola virus epidemic have been prevented? - http://www.virology.ws/2014...
"I'm not worried about it coming to the US. We can deal with it. I'm really worried that a case will land in a country that can't handle it, and then it will spread there. There are dozens of countries that can't handle this." - Vincent Racaniello
Re: Could the Ebola virus epidemic have been prevented? - http://www.virology.ws/2014...
"You are right on that. If we do make infectious diseases national security issues, then research on them can't be controlled by the DOD." - Vincent Racaniello
Re: Could the Ebola virus epidemic have been prevented? - http://www.virology.ws/2014...
"The article did not discuss this issue at all. When a cover does that it's disingenuous." - Vincent Racaniello
Could the Ebola virus epidemic have been prevented? - http://www.virology.ws/2014...
TWiV 304: Given X, solve for EBOV - http://www.virology.ws/2014...
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