"The production of new proteins can only occur when the RNA that will make the required proteins is turned on. Until then, the RNA is "locked up" by a silencing molecule, which is a micro RNA. The RNA and micro RNA are part of a package that includes several other proteins...When synapses got activated, one of the proteins wrapped around that silencing complex gets degraded." When the signal comes in, the wrapping protein degrades or gets fragmented. Then the RNA is suddenly free to synthesize a new protein."
- bob
from Bookmarklet
"The submarine-based Bulava (Mace) missile has been billed as Russia's newest technological breakthrough to support its nuclear deterrent, but the repeated test failures are an embarrassment for the Kremlin. The missile failed in its 13th test on Wednesday morning, Russia's leading economic dailies Vedomosti and Kommersant reported on Thursday, quoting sources in the military-industrial complex. Hours later, the Defense Ministry admitted the failure, saying the launch had been made by the Dmitry Donskoi nuclear submarine from a submerged position in the White Sea. "It has been established ... that the missile's first two stages worked as normal, but there was a technical malfunction at the next, third, stage of the trajectory," a Defense Ministry spokesman said."
- bob
from Bookmarklet
"KINGSTON, Jamaica (AP) - An American Airlines flight carrying 154 people skidded across a Jamaican runway in heavy rain, bouncing across the tarmac and injuring more than 40 people before it stopped just short of the Caribbean Sea, officials and witnesses said. Panicked passengers screamed and baggage burst from overhead bins as Flight 331 from Miami careened down the runway in the capital, Kingston, on Tuesday night, one passenger said. The impact cracked open the fuselage, crushed the left landing gear and separated both engines from the Boeing 737-800, airline spokesman Tim Smith said."
- bob
from Bookmarklet
It has winglets, doesn't seem all that old to me. Planes just aren't designed to land like that one did.
- Alex Scoble
I heard on CNN that the passengers were clapping at the smooth landing before the accident. This runway has poor drainage, so the plane's brakes may have been ineffective. The bouncing and damage may have happened after it left the tarmac. I don't know whether the report I heard or this article (citing turbulence) is accurate. Wait for RISKS Digest.
- Bruce Lewis
from fftogo
And the break pattern seems consistent with the nose, fuselang and tail being separate components
- Deepak Singh
Roberto: The 737-800 has only been around since 1997, so the plane couldn't be more than 12 years old.
- Gabe
See http://www.maxtrescott.com/max_tre... for an AFAICT purely speculative suggestion of what may have happened. Anyway the simplest explanation now is that it broke up because it ran off the runway. Why did it run off the runway? Good question.
- Daniel Dulitz
Running off the end of an 8700 foot runway takes more than one or two factors...
- Daniel Dulitz
Ok not so old then. I wonder what the crash investigation will turn up.
- Roberto Bonini
from iPhone
On CNN a pilot said that this runway lacks grooves for drainage. Hydroplaning and the tailwind are two factors. We'll have to see what other factors were involved.
- Bruce Lewis
Philippine volcano on verge of eruption as lava spills down mountain... but villagers are refusing to leave | Mail Online - http://www.dailymail.co.uk/news...
"A rumbling volcano in the Philippines was on the verge of a major eruption today – but thousands of villagers living on its slopes are refusing to leave their homes. Already, 40,000 people have fled the no-go zone around Mount Mayon, which oozed crimson lava during eerie scenes captured last night. But around 3,000 residents, mostly farmers, remain – with some even returning after being evacuated up to three times by authorities."
- bob
from Bookmarklet
"An ambulance was called to the home of Murphy's husband, screenwriter Simon Monjack, following a 911 call. According to the Los Angeles Times, the LAPD has opened an official investigation into the circumstances surrounding Murphy's death. "
- bob
from Bookmarklet
"The operation, as Tom calls it, is not anything special. It is not one of a kind event. It's just a normal practice, and the process is pretty simple: The manager will instruct all employees to stay at their desks, telling them what to do and what to expect at any given time. The Apple Gestapo never handles the communication. They are there, present, supervising the supervisors, making sure everything goes as planned. All cellphones are then taken. Usually, they collect them all at the same time, which means that the process could take a long time. If you need to contact the exterior during the time your cellphone is under examination, you will have to ask for permission, and your call will be monitored. They don't ask for cameras because there are no cameras at Apple: Employees are not allowed to get into the campus with them. If the cellphone is an iPhone, it gets backed up onto a laptop. "In fact, at the beginning they used to say that the iPhones were really their property, since...
more...
- bob
from Bookmarklet
The few times I've visited Apple, I was impressed that they don't let tailgaters in (one badge swipe per employee, guests have to be let in by the receptionist), but I didn't see any security beyond that.
- Amit Patel
...comparing apples and nazis -- er -- oranges, what is the world coming to? .LOLz!
- .LAG liked that
I dunno. Knowing how much pure drivel the tech "media" publish, I have trouble believing this is true.
- EricaJoy
oh no, dan, sorry to hear that. the same thing happened last week to a girl at my dance studio - and her rent money was in the bag that was stolen. she's been looking for a part-time job to earn this month's rent back, but in the meantime ppl at the studio took up a secret santa collection for her. i think sometimes ppl do shitty things (like steal, argh) so that others can rise up and show how much they care about fighting the shitty. but it still sucks to get your stuff stolen. sorry.
- Felicia Yue
"Too much UV penetrating the skin (too pale-skinned under intense sunlight) increases Vitamin D but reduces folate. Lack of folate causes neural tube defects in the fetus, causing such congenital abnormalities as craniorachischisis, anencephalus, and spina bifida, leading to many miscarriages. On the other hand, too little UV penetrating the skin (too dark-skinned under dim sunlight) increases folate but reduces vitamin D. Lack of vitamin D causes skeletal neonatal abnormalities (skull, chest, and leg malformations), rickets being the best known. Again, this causes miscarriages. And so, humans adapt very quickly to solar UV. Prehistoric groups that migrated towards the equator got darker. Prehistoric groups that migrated away from the equator got lighter. But this explanation fails for Europe. Northern Europeans are lighter than everyone to the south (Mediterraneans), to the east (Mongols and east-Asians), to the west (Native Americans across the Atlantic), and to the North (Inuit,...
more...
- bob
from Bookmarklet
Scandinavians ate mostly meat and fish, and they are even 'whiter' than average European: not only they were white-skinned, but also blond. This fact ruins article's theory, isn't it? ;)
- Pavlo Zahozhenko
Could it be that Scandinavians supplement their diet with rice and grains and therefore receive less vitamin D than anyone else at that latitude? They are whiter than the average European primarily because of the sunlight availability which vitamin D from fish does not easily overcome.
- Bill Strathearn
It's too bad that Knol isn't more like Wikipedia where anyone can edit -- I would trust it more ironically.
- Paul Buchheit
Yes, Paul, but is ironic trust what they're really going for here?
- Cliff Gerrish
Blonde people are blonde because of the Gulf Stream. Also, notice that the graphic on the right has been changed in the live Knol. Blonde people are now represented by a light tan rather than blue.
- Kevin Fox
I thought Google shut down Knol on October 27, 2009. Wait...
- Jérôme Flipo
Yeah, I think I read that on Wikipedia...
- Cliff Gerrish
Paul, I think that open and unrestricted document collaboration works best only when there is a semi-dedicated community of editors to police the content. That exists in Wikipedia, but is hard to replicate elsewhere. Full disclosure: I lead the Knol team and am the majority code contributor.
- Bill Strathearn
I found this article very interesting, and well written to boot.
- Will Higgins™
"Thousands of spectators and surfers are flocking to Hawaii's beaches to see the biggest waves in years crash ashore. Heavy traffic backed up for miles yesterday along roads leading to Oahu's North Shore. Some of the world's most daring surfers took on the powerful and dangerous waves, which forecasters say could reach heights of 50ft (15 metres) by tomorrow."
- bob
from Bookmarklet
"The government wants to carry out what is believed to be the biggest-ever roundup of wild horses on federal land, moving as many as 25,000 mustangs and burros to pastures in the Midwest and East out of fear their fast-multiplying numbers will lead to mass starvation... The government argues that the mustang population in 10 Western states is growing so rapidly that the horses are quickly running out of food, in part because of drought ravaging the region." - it seems like the sort of problem that works itself out (mostly shared for picture)
- bob
from Bookmarklet
"Police believe he fled to Canada and then, a few weeks ago, came back across the border to Idaho where he stole a Cessna 182 and flew to Seattle. He crash-landed in a forest clearing and walked away with cuts and bruises. ... Since then he has been accused of stealing other planes for hops around the islands in the Puget Sound, including another Cessna belonging to a disc jockey who vented his frustration on radio, saying: “He still doesn’t know how to land a plane in one piece.” He evaded a police pursuit by crashing a Mercedes-Benz into a roadside gas storage tank, using the explosion as a diversion to escape back into the woods where, he says, he feels like a Native American....Kohler said she was proud her son had stolen the aircraft because he had never had a flying lesson in his life. “I was going to send him to flight school, but I guess I don’t have to,” she said. “I’d tell him the next time he took a plane: wear a parachute and practise your landing. "
- bob
from Bookmarklet
Awesome. "Kohler said she was proud her son had stolen the aircraft because he had never had a flying lesson in his life"
- Paul Buchheit
I smell a Spielberg bio-pic movie in the future.
- Ray Cromwell
"The game is also more than happy to bribe players for participating in its viral spread: cute lonely animals will show up on your farm periodically and as a player you face a dilemma in sentencing them to virtual abandonment and death unless you post on your Facebook wall that you need one of your friends to start playing Farmville and "adopt" the adorable little self-promoter. "
- bob
True - these things are popular and addictive, but hardly social and you don't learn anything. (And I would have said so as a comment on the blog post, but woo-wee that's a lot of information they want for a registration!)
- Ciaoenrico
I'd have not problem sentencing an IMAGINARY animal to the death chamber. It's make believe! Then again, I don't spend my time playing these silly time wasting games either....
- Jeff P. Henderson
Nice review. Now I don't have to figure out what Farmville is :)
- Peng-Toh
"Thorium is readily available & can be turned into energy without generating transuranic wastes. Thorium's capacity as nuclear fuel was discovered during WW II, but ignored because it was unsuitable for making bombs. A liquid-fluoride thorium reactor (LFTR) is the optimal approach for harvesting energy from Thorium, and has the potential to solve today's energy/climate crisis. This 16 minute video is summarizes 197 minutes worth of Google Tech Talks on the subject of Thorium & LFTR."
- bob
from Bookmarklet
"The pollucite ((Cs,Na)2Al2Si4O12·2H2O) deposit associated with the pegmatite is the largest known deposit of this mineral and with 350,000 tons,[3] it accounts for two thirds of the known resources.[4] With an estimated average global use of 30,000 kg/year the reserves of the mine would last for 2,000 to 3,000 years.[4] The mined pollucite contains approximately 24% Cs2O.[5] The ore body is 1400 m long, 600 m wide and 100 m deep.[6][3] For several decades the pegmatites at Bernic Lake have supplied the world with the needed caesium."
- bob
from Bookmarklet
"Using ultrasound to examine the vessels leading in and out of the brain, Dr. Zamboni made a startling find: In more than 90 per cent of people with multiple sclerosis, including his spouse, the veins draining blood from the brain were malformed or blocked. In people without MS, they were not. He hypothesized that iron was damaging the blood vessels and allowing the heavy metal, along with other unwelcome cells, to cross the crucial brain-blood barrier. (The barrier keeps blood and cerebrospinal fluid separate. In MS, immune cells cross the blood-brain barrier, where they destroy myelin, a crucial sheathing on nerves.) More striking still was that, when Dr. Zamboni performed a simple operation to unclog veins and get blood flowing normally again, many of the symptoms of MS disappeared. The procedure is similar to angioplasty, in which a catheter is threaded into the groin and up into the arteries, where a balloon is inflated to clear the blockages. His wife, who had the surgery three years ago, has not had an attack since."
- bob
from Bookmarklet
"The new technique also uses a light source to illuminate an object. However, the image is not formed from light that hits the object and bounces back. Instead, the camera collects photons that do not hit the object, but are paired through a quantum effect with others that did."
- Amit Patel
from Bookmarklet
"Not everyone agrees that quantum effects are at work in ghost imaging, though. Baris Erkmen and Jeffrey Shapiro of the Massachusetts Institute of Technology, Cambridge, US, point out in a recent paper that classical physics says light sources produce numbers of uncoordinated photons that are not correlated as Shih suggests. They suspect ghost images might be produced without a quantum link between photon pairs, purely because some photons are just similar."
- bob
"It was soon realized that the correlations between the light beam that hits the camera and the beam that hits the object can be purely classical. If quantum correlations are present, the signal to noise ratio of the reconstructed image can be improved." http://en.wikipedia.org/wiki...
- bob
Balzano said Saturday he isn't targeting Boy Scouts. But given the city's decision in July to lay off 39 SEIU members, Balzano said "there's to be no volunteers." No one except union members may pick up a hoe or shovel, plant a flower or clear a walking path...Balzano said Saturday the union is still looking into the matter and might cut the city a break. "We are probably going to let this one go," Balzano said .
- bob
"These amazing pictures were taken by Anatoly Beloshchin in the cave Cenote Angelita, Mexico. Here’s his description: “We are 30 meters deep, fresh water, then 60 meters deep – salty water and under me I see a river, island and fallen leaves… Actually, the river, which you can see, is a layer of hydrogen sulphide.”"
- April Buchheit
from Bookmarklet
too bad no video, would like to see it flowing
- bob
"Chinese chefs have come up with a way to keep a fish alive while deep frying it! It even keeps trying to breathe while waiting to be eaten and people pick at it!" "In order to keep the carp alive chefs cook its body but wrap its head in a wet cloth to keep it breathing, before covering it in sauce and serving in on a plate."- im not an expert on fish anatomy but it seems like having the bottom 2/3 of your body fried would probably be fatal for the top 1/3 - think its real?
- bob
from Bookmarklet
Wow, that's a stumper of a question! :)
- Susan Beebe
Learn all that you can, be noble, true, humble, love much. Seek wisdom from your family and friends
- Susan Beebe
I would say: pls take a picture of me using your iPhone and post it to Posterous and capture that 12sec video of reincarnation process : )
- victed
from iPhone
I wouldn't need 140 characters: "in whatever you do, strive to do it as well as you possibly can." 64.
- Bren -- feeling merry
from iPhone
Never stop learning, enjoy the little things, cherish friends & family, try your best, keep an open mind, and indulge yourself occasionally.
- Nathan Chase
chase your passions, the rest follows. observe everything. work, love and play hard. change happens. live full and balanced. 3
- Charles Ying
Risk is not an option. And eat your vegetables.
- Micah Wittman
Study Thomas, he has more answers than anyone else you will read.
- Alex Scrivener
Number to a Swiss bank safe containing cash, guns and numerous passports. Yes, it is from a movie.
- Peng-Toh
.....so are we trying to guess the meaning of life here? essentially I think that's what this question boils down to. I only need two characters:
- Ⓐ ☠ slayerboy ☠ Ⓐ
Let's git rid of 140 chars nonsense limid.
- Petr Buben
"Reasonable men adapt to the world around them; unreasonable men make the world adapt to them. The world is changed by unreasonable men."
- Paul Buchheit
Paul, try telling April that next time she is frustrated with you; I'm sure it will help ;)
- Clare Dibble
Just told my son this tonight -- Leave the earth better than the way you found it.
- Joe
"Its not that bad, stop sh*tting yourself, ;)"
- chaz2b
++Leo, that sounds like very useful advice. :)
- Ruchira S. Datta
In the end it really doesn't matter, enjoy it while it lasts, do what makes you happy, try not to sabotage the happiness of others.
- April Russo (app103)
Don’t sweat the small stuff. It’s all small stuff.
- Laura Norvig
"Dear Reincarnated Self: my head is frozen with the Life Extension Foundation. To get cool advice pls unfreeze me at ur earliest convenience."
- Philipp Lenssen
"Dont be afraid to take chances or march to a different beat. In the end only the soul counts, don't sweat the small stuff. Listen, learn."
- Grant Bierman
"Please ask the next generation to increase maximum message length."
- Ray Cromwell
BTW, Commander Data was able to get away with sending only 2 *bits* of information into the future/past to break out of a 'groundhog day' scenario. The message: 3
- Ray Cromwell
There once was a site called Twitter. It was worth a billion dollars...
- Sean Kelly
Exercise every day, learn to program asap. I have discovered a truly marvellous proof that these are the right things to do which this twee
- j1m
"I've finally discovered the secret to a contented and effective life, which for you, begins now. This joy can be yours. Just claim it by t" <snipped by character limit>
- Kurtiss Hare
Search for the will of the creator. Prefer the heaven of love to the hell of power.Every moment is unique.Train empathy. Give. [ yeah, I kept in the character limit! Twitter is like life sometimes, only, hu, more limitted :-]
- Willi Schroll
L^2>∞ love of life is greater then time and space. Compassion destroys the destroyer peace above me below me around me down me radiate peace
- Robert Higgins
That's easy: Join friendfeed as soon as possible.
- Jim Addz No Value
don't sweat it kid, you just got a do over...
- J. Abdul-Qahhar
H4sIABnpA0sCA+3KOw2AMBQAwB0VTwEeWHFRPhOFEgghdU91kFsvN+Qcb7m2SMcSR4kzpxp72tY7 xjQ3juVpZSq1j8F1Xdd1Xdd1Xdd1Xdd1Xdd1Xdd1Xdd1/327D0m3yMZIHwAA
- Edward Coffey
"Propose multiple solutions to every problem. Or choose your own life."
- Ivo Danihelka
Love always wins. Don't sweat happiness: find joy. (ponders how to translate the "becoming a man" speech from Secondhand Lions into 140 characters...)
- Ladybug Heather
Remember to save often...data and money. Live life like you have a reset button.
- Brian Merriman
It's not just you, they're all crazy. Make as many friends outside the family as you can. You'll want to leave home. Do it. Don't look back. (this is a seriously awesome topic!)
- Lo
Follow your heart. Don't worry about failure because apparently reincarnation is real. Snooches!
- Kevin Fox
Dont let others decide for you what is good and right for you. Not even this message.
- Joelle Nebbe (iphigenie)
Learn your math. Especially Geometry. It will make your coding SO much more compelling!
- Joe Nickence
Well I won't list all 140 but 1 I will is: Do not live your life to live..Live it to die. In other words, prepare for death because all life is about is another chance to get it right so you can end Samsara.
- Merlyn Seeley
"In your past life, you never understood why people liked Twitter."
- Ryan Kaisoglus
Dear new self: whatever you do, don't make all the same mistakes with your life that I did with mine. For example, you should never ever try [MAXIMUM MESSAGE LENGTH REACHED]
- s t e v e
You, are fine. To hell w' 'em if they think you're not pretty/funny/smart/rich enough.
- Summer
Find Stuart Diamond and take his negotiation course when you're 16. Love yourself so you can love others. Also, reincarnation exists, and you were a geek in your previous life.
- Daniel Dulitz
Don't wish for what you aren't. Life will be far more interesting than you could ever expect. Play with the cards you're dealt, and have fun
- Bette Cooper
Call me Stewie, bow now and pay later. Put another coal in the power plant so you can continue watching this homage and choke on the fumes. [140 and referenced Family Guy, ideology, commerce, ecology, choice, and lost will.]
- William 'Bill' McPhe
"Tom Cruise must be stopped. By any means necessary."
- Otto
Otto, you have room to add "--your mission, if you choose to accept it."
- Micah Wittman
Life is all about ass. You're either covering it, kicking it, kissing it, busting it, laughing it off, or trying to get a piece of it.
- Mona Nomura
Be kind to animals, nature, others & yourself. Do what you love. Love what you do. Never stop learning about the world around you.
- Bronson Harrington
Try to find the 140 characters you would pass along to your reincarnation.
- Eszter Susánszky
"Sodium layer refers to a layer within the Earth's mesosphere of unbound, non-ionized atoms of sodium. The altitude of this layer is usually located between 80–105 km (50–65 miles) and has a depth of about 5 km (3 miles). Atmospheric sodium below this layer is normally chemically-bound in compounds such as sodium oxide, while above the layer the atoms tend to be ionized. Atoms of sodium in this layer are typically in an excited state, and radiate weakly at a wavelengths around 589 nm, which is in the yellow portion of the spectrum. These radiation bands are known as the sodium D lines. The resulting radiation has been termed night glow."
- bob
from Bookmarklet
A love-struck buck ran out of luck a week ago. The seven-point buck was killed when it rammed a 640-pound concrete statue of an elk in the backyard of Mark and Carol Brye's home in rural Viroqua....Brye said he knew exactly what happened when he saw the statue tipped over. Although they were about the same height, the statue weighed at least three times more than the 180-pound deer. He didn't realize the buck lay dead a short distance away. "I could tell the buck poked the statue a couple of times by the chipped paint on it," Brye said, adding that the buck eventually rammed it like a mountain goat. The buck apparently staggered about 20 feet and fell. Brye claimed the buck with a tag from the Vernon County conservation warden. He laughed at the warden's tag note: "lawn ornament fight - lost."
- bob
from Bookmarklet
for some reason the image didnt get through, click on link to see
- bob
"You looking at me? Yeah you! you looking at me punk? I'll teach you to look at me that way!" Famous last words.
- Rasmus Lauridsen
"It doesn't look like much from the outside—just a drab, 10-story building on the campus of Lawrence Livermore National Laboratory, about an hour's drive east of San Francisco....But the reason the building we're in is so huge—it covers the area of three football fields—is that it contains an enormous laser, or actually a system that combines 192 identical lasers and zaps them into a round chamber, about 30 feet in diameter, where the tiny pellet of fuel awaits the blast. NIF's laser, which took a decade to build and was completed earlier this year, can produce 60 times more energy than any other laser ever built. Right now it's still being tested. But next year Moses and his scientists will fire it up with a full load of deuterium-tritium fuel, and Moses feels confident it will achieve "ignition," meaning a controlled burn in which you get out more energy than you put in."
- bob
from Bookmarklet