I guess I'm feeling weird about my conflicted, cautious initial reaction to Angelina Jolie's op-ed. But in the end, if anyone who has a strong family history of breast or ovarian cancer is now motivated to get more in-depth testing or even if you don't have a family history and now decide to get regular screening, that's a good thing.
While I think it's a travesty that Myriad was allowed to literally patent the genes and keep the price for testing high for decades, I also don't think everyone should get tested. At least, it shouldn't be an automatic decision. The pros and cons should be discussed with a healthcare professional. And there are most definitely cons. The probability of inconclusive testing and the resultant anxiety from that uncertainty are just a few.
- Victor Ganata
I started thinking of this as a board question: Consider two women, Ann and Beatrice, in their late 30s. Both women have mothers who died from metastatic breast cancer at an early age, both have young children, and both discover they have an allele of BRCA1 that is correlated with a much increased risk for developing breast cancer, although Ann's mutation is estimated to have a lifetime risk of 56% by age 70 and Beatrice's is estimated to have a lifetime risk of 87% by age 70….
- Victor Ganata
…Ann decides to get prophylactic bilateral mastectomies. Beatrice opts for close surveillance alternating mammograms and breast MRIs every six months. Which woman made the right decision?
- Victor Ganata
Answer: A. both women made the right decision after considering their own personal circumstances and discussing their options with qualified professionals, including a genetic counselor. And it would still be the right decision even if their lifetime risk were identical B. unless you are Ann, Beatrice, or the primary care physician, breast surgeon, oncologist, or genetic counselor who is caring for either of these women, who the hell cares what you or I think?
- Victor Ganata
I think the one of the worst possible outcomes would be if insurance companies decided to pay only for prophylactic bilateral mastectomies but not for lifetime close surveillance. Or vice-versa.
- Victor Ganata
Can you explain the restriction to me? I don't understand it.
- Cristo
Cristo, it's so people aren't wearing 2-3 devices to cheat their friends. I know you like being at the top of the leaderboards, but that's a lame way to do it. More intelligently they would dedupe to one device's data stream if multiple were being used over the same period, and allowing gaps to be filled.
- Jimminy IS Everybody
Yeah, you figured me out. My ego is completely tied up in Fitbit steps. Seriously, I'm sure there are timestamps associated with a set of steps, so you would just take the packet with the most steps and discard the other one. This just makes it more likely I'll return the Flex after I've tried it for a few days. Of course, this means I have to re-setup the One now and wait for the annoying beginner mode to stop (about a week of using it).
- Cristo
The wristband is extremely difficult to put on. I haven't been able to do it yet.
- Cristo
Flex is going back tomorrow. :( All boxed up again. Too bad I popped those packing bags.
- Cristo
Reinstalled the Fitbit One. I was wearing it today and now its fallen out of the stupid rubber case, so now I have no tracker.
- Cristo
"So in July 2011, Vuick banned anyone under six, citing it as the best decision he’s made. “I’ve gotten an overwhelming response from people all over the world, and it’s a thousand to one in favor of what we’ve done. Every day a customer seeks me out to thank me for the policy, or someone writes to tell me they wish a restaurant near them would institute this policy. Business is up and it’s even helped me get some staff I wouldn’t have otherwise attracted.” Some restaurateurs have a different strategy, like Allen Routt, chef and co-owner of The Painted Lady in Newberg, Ore., where children are not banned, but guests are encouraged to leave children under seven at home due to the length of the meal (around three hours) and the mature menu (a multi-course tasting menu). “My restaurant isn’t for some adults, and it’s not for some children,” admits Routt. “But banning children seems like a knee jerk reaction. We are raising the next generation and if we can expose children to manners and...
more...
- Eric - seven eleven
from Bookmarklet
When the title asked, "All children?" I thought they meant *all* children. If the question only refers to little kids, well, that's a different question entirely.
- Betsy #TeamMonique
It's only relatively recently that American restaurants who banned women dropped that practice. "In May 1970 a prominent NYC editor, a woman, walked into Schrafft’s on the corner of 47th Street and Third Avenue with another woman. They noticed that at the back of the restaurant there was a section that looked especially attractive, with more space between tables, tablecloths, and...
more...
- Micah
I think it's fine for fine-dining restaurants to ban kids, especially under a certain age. I know not all kids misbehave or are loud (my cousin was always super quiet and polite), but a long wait for food and a setting that isn't intended for kids can test their patience.
- Heather
RT @dreeandree: Step 1 to a no carb diet: eat all the carbs in your house, ok I'm good at that, but step 2 is don't buy more carbs and that's where I fail.
I think I have 7-8 pounds of rice, a few boxes of instant stuffing, a few boxes of cornbread mix... It would take me quite a while to finish the carbs in my pantry even if I ever did decide this would be a good plan. #teamCarbs
- Andrew C (✓)
from Android
... plus the pasta/dried noodles too. >_>
- Andrew C (✓)
I couldn't give up carbs unless I was forced to. Carbs and meat. And cheese. I need them.
- Anika
My plan for cutting candy out of my diet is to finish the candy in the house. I've found that there's ALWAYS candy in the house!!!!
- Yvonne
from FFHound!
Thank you. I'll have to look up what they have done. Holly, did you see that Stumptown will roast to your request? I just read that this week.
- Mary Carmen
My mother was from Atlantic City if that allows for her use of this acronym. Or having a five year old ask what is a "whore" bath. I will leave the hiney song for another post.
- Janet:#TeamMonique
from FFHound!
Until I read the comments here, I would have assumed the same thing as Soup. I thought it was about the Parent Teacher Association holding a fundraising car-wash. Now that I've seen the comments, though, I realize it's a totally different thing.
- DAMMIT, MR. NOODLE
I guess I could have given some context but it's more interesting this way. :-)
- c.a.j.
from Android
"Is Yahoo trying to acquire Tumblr? Earlier today, All Things D reported that the two companies were in "serious" talks about some kind of deal, and now Adweek is saying that Yahoo is looking to do a straight-up acquisition. The deal could reach as high as $1 billion, say Adweek’s sources, putting it in the same league as Facebook’s acquisition of Instagram last year. Yahoo has been working to capture younger users — the same 18- to 24-year-olds that make up Tumblr’s core user base. Yahoo CFO Ken Goldman recently noted that one of the company’s challenges has been its aging demographic, writes All Things D. Since taking control of Yahoo, CEO Marissa Mayer has pursued a string of acquisitions, including Summly, Astrid, Jybe, and others. In addition to the failed Dailymotion acquisition, the company has also been rumored to be looking at Hulu, although Mayer has previously said that the company is shopping for smaller targets valued in the $100 million range."
- Me
from Bookmarklet
1 Billion is the new go to number for purchases.
- Me
Given their track record with Flickr, Upcoming and other purchases, maybe they better concentrate on cleaning up their backyard first.
- Spidra Webster
why, when they can cover everyone else's yards with carcasses and dog poop too?
- Joe "Bad Guts" Silence
That's a little unfair, in my opinion. The company has had no direction since Yang took over back in 2007, until Marissa Mayer got there. Thompson may have had a chance, but he didn't have a CS degree. Through the changes they've made in the last year and the purchases they've made or attempted to make, they're trying to become a powerhouse media company.
- Jimminy IS Everybody
I guess it kind of depends on how the merger is done. Would Tumblr be allowed to thrive as its own thing, but with some integration into Yahoo, like Flickr (well, hopefully doing better than Flickr)? Or would Tumblr be strip-mined to build stuff elsewhere at Yahoo, more like Facebook's acquisition of Friendfeed? Also, will Tumblr make Yahoo seem cool, or will Yahoo make Tumblr seem stodgy? I don't think the answers are clear-cut.
- John (bird whisperer)
Yahoo could turn it into something like Google+! Um, no. If true, I may move my tumblr to Wordpress.
- Yo. Shark Dog.
John, with such a large size, it would be most likely to go with the Flickr route. You don't can big companies, especially at $1B cost; at that point you're not buying the technology or staff. The better FB parallel would be Instragram.
- Jimminy IS Everybody
NOOOOOOOOOOO... Oh, wait. John said that already. KHHHAAAAAAAAAAAAAAANNNN!!!
- Steven Perez
from Android
"In 2011, Alcatel-Lucent had American e-commerce on the ropes. The French telecom had sued eight big retailers and Intuit saying that their e-commerce operations infringed Alcatel patents; one by one they were folding. Kmart, QVC, Lands' End, and Intuit paid up at various stages of the litigation. Just before trial began Zappos, Sears, and Amazon also settled. That left two companies holding the bag: Overstock.com and Newegg, a company whose top lawyer had vowed not to ever settle with patent trolls. "
- Andrew C (✓)
from Bookmarklet
"Then things started going badly for the plaintiff. Very badly. Instead of convincing the East Texas jury to hand Alcatel the tens of millions it was asking for--$12 million from Newegg alone--the company got a verdict of non-infringement. And as for the one patent Alcatel had argued throughout trial was so key to modern e-commerce--US Patent No. 5,649,131--the jury invalidated its claims."
- Andrew C (✓)
"Federal Circuit judges typically take months, and occasionally years, to review the patent appeals that come before them. Briefs in this case were submitted last year and oral arguments were held May 10. The three-judge panel upheld Newegg's win without comment--in just three days."
- Andrew C (✓)
And this is why I continue to give my money to Newegg. Fuck. Yes.
- Hookuh Tinypants
Makes the legal departments at Amazon, Sears, Kmart, QVC, etc look pretty bad.
- Andrew C (✓)
from Android
"The new cast is still disconcerting. By the end of the original Trek, the actors were a collection of paunches and hairpieces; these guys are so trim and tender-skinned, they're like the Baby Looney Tunes."
- MoTO #TeamMonique
from Bookmarklet
Good straw man. Shows you being ignorant of what I actually said.
- Jimminy IS Everybody
Except it's not a straw man at all, Jimminy. That's exactly what Johnny is doing. I'm sure he's trying to be funny, but not really succeeding. And once again, this is not about you.
- Scoble, Alex Scoble
I mean, come on, Jimminy, you aren't one of the people getting left behind, you are one of the people leaving others behind you.
- Scoble, Alex Scoble
Alex, but for the OP the same could be said about the negatives of a technology or product. The individual doesn't have to be ignorant to the benefits to still decide not to use it.
- Jimminy IS Everybody
Alex, possibly, but even if I was I don't care. I'm always going to be left behind in some fashion, even if I'm leading in others.
- Jimminy IS Everybody
Wait. So, this isn't related to the fact that Adobe isn't selling physical copies of their Creative Suite anymore? :P
- DAMMIT, MR. NOODLE
I'm not ignoring the benefits. Believe it or not I have 3 exceptional use cases for the technology... but I'm not slobbering over it with froth'd mouth like this will change everything. I get the passion, I don't get the blow back cause I don't share that passion like I'm somehow missing the point or a luddite. Technology won't save us, our proper use of said technology will. Blind faith in technology is misguided
- Johnny
from iPhone
I'm not slobbering over it either because A) it's too damn expensive B) not particularly useful to me yet 3) my brother in the shower iiii) racecar. If you at least have the vision to see where this technology could lead, then we really have no quibbles. The great thing about technology is that it usually works regardless of whether you think it will.
- Scoble, Alex Scoble
"Proving once and for all that there is no Kickstarter project so silly that people won't throw money at it, funny New Yorker Kurt Braunohler was able to successfully raise nearly $7,000 for his campaign to write funny words in the sky."
- Me
from Bookmarklet
"ThinkGeek has released this set of Marvel Superhero Family Car Decals, a delightfully geeky way to show your love of Marvel’s Iron Man, Spider-Man, Captain America and Wolverine characters. They come in packs of 50 (including pet versions of each superhero) and are available to purchase online."
- Spidra Webster
from Bookmarklet
Looking at who is directing all the interesting-looking (to me, at least) science fiction movies coming out this year, it really does seem like non-U.S. sensibilities are going to be the mainstay of the future.
"Looks like the 2013-2014 television season will be a rebuilding year for SNL. An unnamed source at NBC has confirmed to the New York Post that longtime castmember Fred Armisen has decided to exit the sketch show after 11 seasons. That same source tells the Post that SNL veteran Jason Sudeikis will “probably” leave the show as well this year."
- Surprisingly Monstrous
from Bookmarklet
"If Armisen and Sudeikis do say goodbye in SNL‘s 38th season finale this weekend, they’ll join fellow departing cast member Bill Hader, who announced his own exit earlier this week. SNL‘s Weekend Update anchor Seth Meyers is also leaving the show, albeit not until 2014"
- Surprisingly Monstrous
Oh. They meant "out of the show". I totally thought the headline meant "out of the closet together"
- DAMMIT, MR. NOODLE
Jason Sudeikis is engaged to Olivia Wilde so if i was him i'd wait for that to fall apart before coming out of the closet.
- Surprisingly Monstrous
Followed only by "Wife might comment on it" and "Waif might laugh at it"
- Pete #TeamMonique
Me mudder is a luddite, Uli. But someone might "tell" her about it. Your scenarios are a given part of my daily life, Pete. They mock me constantly. Though I do make it easy.
- MoTO #TeamMonique
And yet you get to share your life with them. Seems a fair swap :)
- Pete #TeamMonique
I'm sure my mom is happy to tell Barry's mom what's up with little Moto.
- Steele Lawman
TELL HER I'M EATING ALL MY VEGETABLES, MAMA LAWSON!
- MoTO #TeamMonique
I always figure if it would mortify my grandmother, I probably shouldn't do it. That doesn't always stop me, but it's a little something to think about.
- Katy S
Lifesize cardboard cutouts are surprisingly reasonably priced. http://www.shindigz.com/party... Don't say I never gave you anything interesting, FriendFeed
We got a lifesize Bilbo Baggins cutout at work. Lifesize for a hobbit is short! Made me laugh. I got dibs on it and took it home after we were done with it, so it's coming with me to a convention soon. I hope it finds a good home.
- Betsy #TeamMonique
How has Mr 42 never made one of these of himself?
- sglassme
I don't know! He must not know how cheap they are!
- Sarah G.
My college roommate and I had a lifesize Frugal Gourmet in our dorm room. Why? Because we found him near the trash one night, so brought him home. We were probably drunk when we did.
- ellbeecee
Well they are "from" $19. Probably to get one that is 6'4" will be a bit more than that.
- sglassme
We have a Sarah Michelle Gellar from Buffy days that comes out on special occasions. She is taller than me in it, and I'm over 6'
- Surprisingly Monstrous
Love Supernatural, but I think it should have ended when the creator wanted it to end...like two-three seasons ago.
- Shevonne
Let's hope they don't go the way of Smallville. That completely sucked at the end.
- Todd Hoff
While it is a rather different show than it was seasons 2-5, I still think they've done a great job with it. I hope they can keep it going that way for 2 more seasons.
- DAMMIT, MR. NOODLE
Mother would call the alternative to showering the PTA sink bath. You can figure out the acronym.
- Janet:#TeamMonique
from FFHound!
Janet, my mother says the same thing. that's too funny. also, once I was hanging out with friends for an all-day festival thing,we made a pit stop at my house which was closest so we could all use the bathroom. when I got back in the car my friend said "did you just put some perfume on to cover your stink?" I admitted I had. She says, "you are southern aren't you?" 0_O
- t-ra: not givin up
Today I'm taking a bus ride with a reporter who's living in and writing about East Oakland for the Tribune. He's not from here & wants to learn about Oakland as it was, how it's changed. I'm excited to be part of his project but I hope he doesn't want to take pictures of me :-)
Sounds like fun. He's in for a treat spending the day with Mandy.
- MoTO #TeamMonique
:-) our buddy George Kelly made the introduction, B. Honored he thought of me, but worried I won't be interesting, lol.
- Starmama
from FFHound(roid)!
Oh thats a nice story line there.. I just spent 15min on the entry "Felix the Cat" !!
- Peter Dawson
Felix Mitchell has become Oakland's version of a Stagolee-type outlaw hero (I was a teenager but I thought his funeral was a shameful spectacle. Most Oaklanders feel the same way). He spread money around the hood, yeah, but he was a lowlife crook.
- Starmama
from FFHound(roid)!
It was fun, just a bus ride chatting about Oakland with a nice guy & a photog taking pictures. I don't know what he's gonna get out of my ramblings, but it should be published I think tomorrow, so we shall see :-)
- Starmama
from FFHound(roid)!
Give George my best, Mandy. Not having any luck with the article on my Nook. Will check tumblr in a bit.
- MoTO #TeamMonique
from Android
I hate the way I look on the videos, all that fat isn't on my face when I look in the mirror.
- Starmama
from FFHound(roid)!
“I like the evolution,” she said, “I get nostalgia for the way things used to be — I’d go into that Rexall and my mom would buy me a coloring book if I was good — but change is good, too.” And this ladies and gentlemen is one of the reasons I love Mandy so.
- MoTO #TeamMonique
Ha, he didn't include what I said about the Rexall now being a Mexican grocery with bins of nopales outside - which led to my "change is good" comment :-)
- Starmama
from FFHound(roid)!
the article came out lovely. so cool of you to share yourself like that. cheers!
- t-ra: not givin up
I think it would be pretty hard to win a fight against a guy with a time machine, let alone a guy with a time machine *and* a sonic screwdriver. How are you going to threaten a guy with a Death Star when he can just go back in time and make sure your Death Star isn't even built?
- Victor Ganata
And now I just realized why R2D2 can open *any* door and hack into *any* computer. Some mad scientist has apparently fused together a Dalek with a Time Lord.
- Victor Ganata
"At Ford and elsewhere, a common response to the brutal intensification of work was absenteeism and high quit rates: in 1913, Ford's daily absentee rate was 10 percent, while annual turnover exceeded 350 percent. To reduce turnover, which was costly to the company, Ford doubled the daily wages of his most valued employees, to five dollars a day. This strategy was successful in stabilizing the labor force and reducing operating costs"
- MoTO #TeamMonique
from Bookmarklet